Reaction Details
Reaction: Thumb
L-serine + a tetrahydrofolate ↔ glycine + a 5,10-methylene-tetrahydrofolate + H2O
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:GLYOHMETRANS-RXN
References:
  • Akhtar M, el-Obeid HA (1972). "Inactivation of serine transhydroxymethylase and threonine aldolase activities." Biochim Biophys Acta 258(3);791-9. PMID: 5017703
  • Blakley RL (1960). "A spectrophotometric study of the reaction catalysed by serine transhydroxymethylase." Biochem J 77(3);459-65. PMID: 16748851
  • Fujioka M (1969). "Purification and properties of serine hydroxymethylase from soluble and mitochondrial fractions of rabbit liver." Biochim Biophys Acta 185(2);338-49. PMID: 5808700
  • Kumagai H, Nagate T, Yoshida H, Yamada H (1972). "Threonine aldolase from Candida humicola. II. Purification, crystallization and properties." Biochim Biophys Acta 258(3);779-90. PMID: 5017702
  • Schirch L, Gross T (1968). "Serine transhydroxymethylase. Identification as the threonine and allothreonine aldolases." J Biol Chem 243(21);5651-5. PMID: 5699057