| Identification |
| Name: |
serine hydroxymethyltransferase |
| Synonyms: |
Not Available |
| Gene Name: |
glyA2 |
| Enzyme Class: |
Not Available |
| Biological Properties |
| General Function: |
cellular amino acid metabolic process, glycine metabolic process, lysine catabolic process, L-serine metabolic process, threonine metabolic process, methane metabolic process |
| Specific Function: |
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity, glycine hydroxymethyltransferase activity, catalytic activity, pyridoxal phosphate binding |
| Cellular Location: |
Cytoplasmic |
| KEGG Pathways: |
|
| KEGG Reactions: |
Not Available |
| SMPDB Reactions: |
Not Available |
| PseudoCyc/BioCyc Reactions: |
| L-serine + a tetrahydrofolate ↔ glycine + a 5,10-methylene-tetrahydrofolate + H 2O ReactionCard |
|
| Complex Reactions: |
Not Available |
| Transports: |
Not Available |
| Metabolites: |
Not Available |
| GO Classification: |
| Function |
|---|
| 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity | | glycine hydroxymethyltransferase activity | | catalytic activity | | pyridoxal phosphate binding | | Process |
|---|
| cellular amino acid metabolic process | | glycine metabolic process | | lysine catabolic process | | L-serine metabolic process | | threonine metabolic process | | methane metabolic process |
|
| Gene Properties |
| Locus tag: |
PA2444 |
| Strand: |
- |
| Entrez Gene ID: |
882925 |
| Accession: |
NP_251134.1 |
| GI: |
15597640 |
| Sequence start: |
2742401 |
| Sequence End: |
2743657 |
| Sequence Length: |
1256 |
| Gene Sequence: |
>PA2444
ATGTTCAGCAAGCACGACCAGCTCCAGGGCTACGACGACGAACTGCTCGCCGCGATGGACGCCGAAGACCGGCGGCAGGAAGACCACATCGAACTGATCGCCTCGGAGAACTACGCCAGCAAGCGGGTCATGCAGGCGCAGGGCGGCGGCCTGACCAACAAGTATGCCGAGGGCTATCCGGGCAAGCGTTACTACGGCGGCTGCGAACACGTCGACAAGGTCGAGCGGCTGGCCATCGACCGCGCCAGGCAACTGTTCGGCGCCGACTACGCCAACGTCCAGCCGCACTCCGGTTCCTCGGCCAACGCTGCGGTGTACCTGGCGCTGCTCAACGCCGGCGACACCATCCTCGGCATGAGCCTGGCCCACGGCGGCCATCTCACCCACGGCGCCAAGGTGTCCTCCTCCGGCAAGCTGTACAACGCCGTGCAGTACGGCCTGGACACCGCTACCGGGCTGATCGACTACGACGAAGTCGAGCGCCTGGCCGTGGAGCATAAGCCGAAGATGATCGTCGCCGGCTTCTCCGCCTACTCCAAGACCCTCGACTTCCCGCGCTTCCGCGCCATCGCCGACAAGGTCGGCGCGCTGCTGTTCGTCGACATGGCCCACGTCGCCGGGCTGGTCGCCGCCGGCCTCTACCCGAACCCGATCCCCTTCGCCGACGTGGTCACCACCACCACCCACAAGACCCTGCGCGGCCCGCGCGGCGGCCTGATCCTGGCGCGCGCCAACGAGGAGATCGAGAAGAAGCTCAACTCCGCGGTATTCCCCGGCGCCCAGGGCGGCCCGCTGATGCACGTGATCGCGGCCAAGGCGGTGTGCTTCAAGGAAGCGCTGGAGCCGGGCTTCAAGGACTACCAGGCGCAGGTGATCCGCAACGCCAAGGCGATGGCCGAGGTGTTCATCGGGCGCGGCTACGACGTGGTTTCCGGTGGCACCGACAACCACCTGATGCTGATCAGCCTGGTGAAGCAGGGGCTGACCGGCAAGGCCGCCGACGCGGCGCTCGGAGCGGCGCACATCACGGTGAACAAGAACGCCGTGCCGAACGATCCGCAGAGCCCGTTCGTCACCTCCGGCATCCGCATCGGCACCCCAGCGGTGACCACTCGCGGTTTCCGCGAGGGCGAGTGCCGAGAACTGGCTGGCTGGATCTGCGACATCCTCGACGATATCGACAATCCCGAGGTCGGCGAACGGGTCAGGGGCCAGGTCGGCGAATTCTGCCGGCACTTCCCGGTCTACGCTGATTGA |
| Protein Properties |
| Protein Residues: |
418 |
| Protein Molecular Weight: |
45 kDa |
| Protein Theoretical pI: |
6.51 |
| Hydropathicity (GRAVY score): |
-0.169 |
| Charge at pH 7 (predicted): |
-3.78 |
| Protein Sequence: |
>PA2444
MFSKHDQLQGYDDELLAAMDAEDRRQEDHIELIASENYASKRVMQAQGGGLTNKYAEGYPGKRYYGGCEHVDKVERLAIDRARQLFGADYANVQPHSGSSANAAVYLALLNAGDTILGMSLAHGGHLTHGAKVSSSGKLYNAVQYGLDTATGLIDYDEVERLAVEHKPKMIVAGFSAYSKTLDFPRFRAIADKVGALLFVDMAHVAGLVAAGLYPNPIPFADVVTTTTHKTLRGPRGGLILARANEEIEKKLNSAVFPGAQGGPLMHVIAAKAVCFKEALEPGFKDYQAQVIRNAKAMAEVFIGRGYDVVSGGTDNHLMLISLVKQGLTGKAADAALGAAHITVNKNAVPNDPQSPFVTSGIRIGTPAVTTRGFREGECRELAGWICDILDDIDNPEVGERVRGQVGEFCRHFPVYAD |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA2444 and its homologs
|
