Reaction Details
Reaction: Thumb
5-phospho-β-D-ribosylamine + ATP + glycine → ADP + N1-(5-phospho-β-D-ribosyl)glycinamide + phosphate + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:GLYRIBONUCSYN-RXN
References:
  • Goldthwait DA, Greenberg GR, Peabody RA (1956). "On the mechanism of synthesis of glycinamide ribotide and its formyl derivative." J Biol Chem 221(2);569-77. PMID: 13357451
  • Hartman SC, Buchanan JM (1958). "Biosynthesis of the purines. XXII. 2-Amino-N-ribosylacetamide-5'-phosphate kinosynthase." J Biol Chem 233(2);456-61. PMID: 13563520