Reaction Details
Reaction: Thumb
GTP + 3 H2O → 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate + diphosphate + 2 H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:GTP-CYCLOHYDRO-II-RXN
References:
  • Foor F, Brown GM (1975). "Purification and properties of guanosine triphosphate cyclohydrolase II from Escherichia coli." J Biol Chem 1975;250(9);3545-51. PMID: 235552