Reaction 21091

Reaction Details
Reaction: Thumb
coproporphyrinogen III + 2 S-adenosyl-L-methionine → protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:HEMN-RXN
References:
  • Layer G, Verfurth K, Mahlitz E, Jahn D (2002). "Oxygen-independent coproporphyrinogen-III oxidase HemN from Escherichia coli." J Biol Chem 2002;277(37);34136-42. PMID: 12114526
  • Layer G, Moser J, Heinz DW, Jahn D, Schubert WD (2003). "Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes." EMBO J 22(23);6214-24. PMID: 14633981