Reaction 21048

Reaction Details
Reaction: Thumb
1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate + H+ → (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:IGPSYN-RXN
References:
  • Creighton TE, Yanofsky C (1966). "Indole-3-glycerol phosphate synthetase of Escherichia coli, an enzyme of the tryptophan operon." J Biol Chem 241(20);4616-24. PMID: 5332729
  • Hutter R, Niederberger P, DeMoss JA (1986). "Tryptophan biosynthetic genes in eukaryotic microorganisms." Annu Rev Microbiol 40;55-77. PMID: 3535653