ATP synthase subunit a (PA5560)

Identification
Name: ATP synthase subunit a
Synonyms:
  • ATP synthase F0 sector subunit a
  • F-ATPase subunit 6
Gene Name: atpB
Enzyme Class: Not Available
Biological Properties
General Function: Involved in hydrogen ion transmembrane transporter activity
Specific Function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
  • Oxidative phosphorylation PW000919
  • adenosine ribonucleotides de novo biosynthesis PWY-7219
  • superpathway of adenosine nucleotides de novo biosynthesis I PWY-7229
  • superpathway of purine nucleotides de novo biosynthesis I PWY-841
  • superpathway of adenosine nucleotides de novo biosynthesis II PWY-6126
    KEGG Reactions: Not Available
    SMPDB Reactions:
    Adenosine diphosphate+Thumb+4 Thumb+Thumb ↔ Thumb+3 Thumb+Thumb
    Adenosine diphosphate + Phosphate + 4 Hydrogen ion + ADP ↔ Water + 3 Hydrogen ion + Adenosine triphosphate
    ReactionCard
    PseudoCyc/BioCyc Reactions:
    Adenosine diphosphate+Thumb+4 Thumb+Thumb ↔ Thumb+3 Thumb+Thumb
    Adenosine diphosphate + Phosphate + 4 Hydrogen ion + ADP ↔ Water + 3 Hydrogen ion + Adenosine triphosphate
    ReactionCard
    Thumb
    ATP + H+[cytosol] + H2O ↔ ADP + phosphate + H+[periplasm]
    ReactionCard
    PAMDB001633+PAMDB110477+PAMDB000142 → PAMDB001633+PAMDB110479+PAMDB110244
    Hydrogen ion + ATP + Water → Hydrogen ion + ADP + phosphate
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB000148Adenosine triphosphateMetaboCard
    PAMDB000345ADPMetaboCard
    PAMDB001633Hydrogen ionMetaboCard
    PAMDB000383PhosphateMetaboCard
    PAMDB000142WaterMetaboCard
    GO Classification:
    Component
    macromolecular complex
    protein complex
    proton-transporting ATP synthase complex, coupling factor F(o)
    proton-transporting two-sector ATPase complex, proton-transporting domain
    Function
    cation transmembrane transporter activity
    hydrogen ion transmembrane transporter activity
    inorganic cation transmembrane transporter activity
    ion transmembrane transporter activity
    monovalent inorganic cation transmembrane transporter activity
    substrate-specific transmembrane transporter activity
    transmembrane transporter activity
    transporter activity
    Process
    ATP biosynthetic process
    ATP synthesis coupled proton transport
    cellular nitrogen compound metabolic process
    metabolic process
    nitrogen compound metabolic process
    nucleobase, nucleoside and nucleotide metabolic process
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
    nucleoside phosphate metabolic process
    nucleotide metabolic process
    purine nucleoside triphosphate biosynthetic process
    purine nucleotide biosynthetic process
    purine nucleotide metabolic process
    purine ribonucleoside triphosphate biosynthetic process
    Gene Properties
    Locus tag: PA5560
    Strand: -
    Entrez Gene ID: 880089
    Accession: NP_254247.1
    GI: 15600753
    Sequence start: 6253542
    Sequence End: 6254411
    Sequence Length: 869
    Gene Sequence: 
    >PA5560
ATGGCAGCAGAAACCGCTTCGGGTTACATCCAGCACCACTTGCAGAACCTGACCTTCGGGCGTCTGCCTAATGGTGATTGGGGGTTCGCCCACACCGCCGAGCAAGCCAAGGAAATGGGCTTCTGGGCATTCCACGTAGACACCCTGGGCTGGTCGGTACTGCTCGGCGTGGTGTTCCTGTTCATCTTCCGCCTGGCAGCCAAGAAGGCCACCAGCGGCCAGCCGGGTGGACTGCAGAACTTCGTCGAGGTGATGGTCGAGTTCGTCGACACCAGCGTCAAGGACACCTTCCACGGGCGCAACCCGTTGATCGCGCCCCTGGCCCTGACCGTGTTCGTCTGGATCTTCCTGCTCAACCTGATCGACCTGGTACCGGTGGACTACCTGCCGATGCTGGCCGCGAAGATCACCGGCGACGAGCACCTGTTCTTCCGCGCGGTGGCCACCACCGACCCGAACGCCACCCTCGGCCTGTCGATCTCGGTGTTCGCGCTGATCGTCTTTTACAGCATCAAGGTCAAGGGCATCGGCGGCTTCCTCGGTGAACTGACCCTGCACCCCTTCAGCAGCAAGAACATCGTCGTTCAGATCCTGCTGATTCCGGTGAACTTCCTGCTCGAGTTCGTGACCCTGATCGCCAAGCCGGTTTCGCTGGCGCTGCGTCTGTTCGGCAACATGTATGCCGGCGAACTGATCTTCATTCTGATCGCCGTCATGTTCGGTAGCGGAATGTTCCTGCTGAGTGCCCTGGGCGTAGCCCTGAACTGGGCGTGGGCTGTGTTCCACATCCTGATCATCACCCTGCAGGCCTTCATCTTCATGATGCTGACCATCGTCTACCTGTCGATGGCGCACGAAGACAACCATTAA
    Protein Properties
    Protein Residues: 289
    Protein Molecular Weight: 31.9 kDa
    Protein Theoretical pI: 6.51
    Hydropathicity (GRAVY score): 0.828
    Charge at pH 7 (predicted): -2.61
    Protein Sequence: 
    >PA5560
MAAETASGYIQHHLQNLTFGRLPNGDWGFAHTAEQAKEMGFWAFHVDTLGWSVLLGVVFLFIFRLAAKKATSGQPGGLQNFVEVMVEFVDTSVKDTFHGRNPLIAPLALTVFVWIFLLNLIDLVPVDYLPMLAAKITGDEHLFFRAVATTDPNATLGLSISVFALIVFYSIKVKGIGGFLGELTLHPFSSKNIVVQILLIPVNFLLEFVTLIAKPVSLALRLFGNMYAGELIFILIAVMFGSGMFLLSALGVALNWAWAVFHILIITLQAFIFMMLTIVYLSMAHEDNH
    References
    External Links:
    Resource Link
    Genome ID: PA5560
    Entrez Gene ID: 880089
    NCBI Protein ID: 15600753
    General Reference: PaperBLAST - Find papers about PA5560 and its homologs