Identification
Name: ATP-dependent DNA helicase recG
Synonyms: Not Available
Gene Name: recG
Enzyme Class:
Biological Properties
General Function: Replication, recombination and repair
Specific Function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. recG unwind branched duplex DNA (Y-DNA). Has a role in constitutive stable DNA replication (csdR) and R-loop formation
Cellular Location: Cytoplasmic
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
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    PAMDB110477PAMDB110479+PAMDB110244
    Complex Reactions:
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    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB000148Adenosine triphosphateMetaboCard
    PAMDB000345ADPMetaboCard
    PAMDB001776Inorganic phosphateMetaboCard
    PAMDB000142WaterMetaboCard
    GO Classification:
    Function
    adenyl nucleotide binding
    adenyl ribonucleotide binding
    ATP binding
    ATP-dependent DNA helicase activity
    ATP-dependent helicase activity
    ATPase activity
    ATPase activity, coupled
    binding
    catalytic activity
    DNA helicase activity
    helicase activity
    hydrolase activity
    hydrolase activity, acting on acid anhydrides
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    nucleic acid binding
    nucleoside binding
    nucleoside-triphosphatase activity
    purine nucleoside binding
    pyrophosphatase activity
    Process
    cellular macromolecule metabolic process
    DNA metabolic process
    DNA recombination
    DNA repair
    macromolecule metabolic process
    metabolic process
    Gene Properties
    Locus tag: PA5345
    Strand: +
    Entrez Gene ID: 880937
    Accession: NP_254032.1
    GI: 15600538
    Sequence start: 6012976
    Sequence End: 6015051
    Sequence Length: 2075
    Gene Sequence:
    >PA5345
    ATGACCGAGCTGTCCAGGGTCCCGGTCACCGCGCTAAAGGGCGTAGGCGCCGCGCTGGCGGAGAAGCTCGCTCGGGTAGGCCTGGAAACCCTGCAGGACATCCTGTTCCACCTGCCCCTGCGCTACCAGGACCGTACCCGCGTCACCGCCATCGGCGCCCTGCGGCCAGGGGCCGACGCGGTGGTCGAGGGCGTGGTGGCCGGCGCCGACGTGGTGATGGGGCGCCGCCGCAGCCTGCTGGTGCGCCTACAGGACGGCAGCGGCACCCTGAGCCTGCGCTTCTACCATTTCAGCCAGGCGCAGAAGGACGGCCTCAAGCGCGGCACCCACCTGCGCTGCTACGGCGAAGTCCGGCCGGGTGCATCGGGCCTGGAGATCTACCATCCGGAATACCGCGCGCTGAACGGCGACGAACCGATTCCGGTGGAGCAGACCCTGACGCCGATCTACCCGACTACCGAAGGACTCACCCAGCAGCGCCTGCGCCAGTTGAGCCAACAGGCCCTGGCCATGCTCGGTCCCAGCAGCCTGCCCGACTGGCTGCCGGCGGAACTGGCCCGCGATTACCAACTTGGCCCGCTCGACCAGGCGATCCGCTACCTGCACCGGCCGCCGCCGGATGCCGACATCGAGGAACTGGCCGAAGGCCGGCACTGGGCGCAGTTGCGCCTGGCCTTCGAAGAACTGCTGACCCACCAGTTATCCCTGCAGCGCCTGCGCGAAGCCGTGCGTTCGCAGGCAGCGCCGCGCTTGCCGGCGGCCAGCCGCTTGCCGAAACGCTTCCTTGCCAACCTCGGCTTCCAGCCGACCGGCGCGCAACGCCGGGTCGGCGCGGAGATCGCCTACGACCTGGCCCAGGACGAACCGATGCTGCGCCTGGTGCAAGGCGACGTCGGCGCCGGCAAGACCGTGGTCGCCGCCCTCGCCGCCCTGCAAGCCATAGAGGCCGGTTACCAGGTGGCGCTGATGGCGCCGACCGAGATCCTCGCCGAGCAGCATTTCCTCAACTTCAGCAAGTGGCTCCAGCCGCTGGACATCGAAGTCGCCTGGCTGGCCGGCAAGCTCAAGGGCAAGGCCCGCGCGGCGGCACTGGAACGCATCGGCGACGGCGCGCCGATGGTGGTCGGCACCCACGCGCTGTTCCAGGATGAAGTGAAATTCAAGCGCCTTGCACTGGCGATCATCGACGAACAGCACCGCTTCGGCGTGCAGCAGCGCCTGGCCCTGCGCCAGAAGGGCGTGGACGGCAGGCTCTGCCCACACCAGTTGATCATGACCGCCACGCCGATCCCGCGGACCCTGGCGATGAGCGCCTATGCCGACCTCGACACCTCGATCCTAGACGAGCTGCCGCCCGGGCGTACCCCGGTGAATACCGTGCTGGTGGCCGACAGCCGCCGTATCGAGGTGATCGAGCGAGTCCGCGCGGCTTGCCGCGAAGGGCGCCAGGCCTACTGGGTGTGCACTCTGATCGAAGAGTCCGAGGAGCTTACCTGCCAGGCCGCCGAGACCACCTACGAAGAGCTTTCCTCGGCGCTAGGCGAACTGCGCGTCGGCCTGATCCACGGGCGCATGAAGCCGGCGGACAAGGCCGTGGTGATGGAAGCCTTCAAGGAAGGCATGTTGCAACTGCTGGTGGCGACCACGGTGATCGAGGTCGGCGTCGACGTGCCCAACGCCAGCCTGATGATCATCGAGAACCCCGAGCGCCTTGGCCTGGCCCAACTGCACCAGTTGCGCGGCCGGGTTGGCCGGGGCAGCGCCGCCAGCCACTGCGTGCTGCTCTACCACCCACCGCTGTCGCAGATCGGCCGCGAGCGGCTGGGCATCATGCGCGAAACCAGCGACGGCTTCGTCATCGCCGAGAAGGACCTGGAATTGCGCGGCCCCGGCGAAATGCTCGGCACCCGCCAAACCGGCCTGCTGCAATTCAAGGTCGCCGACCTGATGCGCGACGCAGACCTGCTGCCGGCGGTCCGCGATGCCGCCCAATCCCTCCTGGCGCACTGGCCGCAGCATGTCAGCCCGCTGCTCGAACGGTGGTTGCGCCACGGCCAGCAATACGGTCAAGTGTGA
    Protein Properties
    Protein Residues: 691
    Protein Molecular Weight: 76.2 kDa
    Protein Theoretical pI: 7.31
    Hydropathicity (GRAVY score): -0.128
    Charge at pH 7 (predicted): 2.19
    Protein Sequence:
    >PA5345
    MTELSRVPVTALKGVGAALAEKLARVGLETLQDILFHLPLRYQDRTRVTAIGALRPGADAVVEGVVAGADVVMGRRRSLLVRLQDGSGTLSLRFYHFSQAQKDGLKRGTHLRCYGEVRPGASGLEIYHPEYRALNGDEPIPVEQTLTPIYPTTEGLTQQRLRQLSQQALAMLGPSSLPDWLPAELARDYQLGPLDQAIRYLHRPPPDADIEELAEGRHWAQLRLAFEELLTHQLSLQRLREAVRSQAAPRLPAASRLPKRFLANLGFQPTGAQRRVGAEIAYDLAQDEPMLRLVQGDVGAGKTVVAALAALQAIEAGYQVALMAPTEILAEQHFLNFSKWLQPLDIEVAWLAGKLKGKARAAALERIGDGAPMVVGTHALFQDEVKFKRLALAIIDEQHRFGVQQRLALRQKGVDGRLCPHQLIMTATPIPRTLAMSAYADLDTSILDELPPGRTPVNTVLVADSRRIEVIERVRAACREGRQAYWVCTLIEESEELTCQAAETTYEELSSALGELRVGLIHGRMKPADKAVVMEAFKEGMLQLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGSAASHCVLLYHPPLSQIGRERLGIMRETSDGFVIAEKDLELRGPGEMLGTRQTGLLQFKVADLMRDADLLPAVRDAAQSLLAHWPQHVSPLLERWLRHGQQYGQV
    References
    External Links:
    Resource Link
    Genome ID: PA5345
    Entrez Gene ID: 880937
    NCBI Protein ID: 15600538
    General Reference: PaperBLAST - Find papers about PA5345 and its homologs