Glycine cleavage system H protein (PA5214)

Identification
Name: Glycine cleavage system H protein
Synonyms: Not Available
Gene Name: gcvH
Enzyme Class: Not Available
Biological Properties
General Function: Amino acid transport and metabolism
Specific Function: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
Cellular Location: Not Available
KEGG Pathways:
  • Glycine, serine and threonine metabolism pae00260
KEGG Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb+Thumb
Glycine + Tetrahydrofolic acid + NAD ↔ 5,10-Methylene-THF + Ammonia + Carbon dioxide + NADH + Hydrogen ion
ReactionCard
Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb+Thumb
NAD + Glycine + Tetrahydrofolic acid → Hydrogen ion + 5,10-Methylene-THF + Ammonia + Carbon dioxide + NADH
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb+Thumb
NAD + Glycine + Tetrahydrofolic acid → Hydrogen ion + 5,10-Methylene-THF + Ammonia + Carbon dioxide + NADH
ReactionCard
Complex Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb
Glycine + NAD + Tetrahydrofolic acid → Carbon dioxide + 5,10-Methylene-THF + NADH + Ammonium
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0003535,10-Methylene-THFMetaboCard
PAMDB000017AmmoniaMetaboCard
PAMDB001595AmmoniumMetaboCard
PAMDB000568Carbon dioxideMetaboCard
PAMDB000046GlycineMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000197NADMetaboCard
PAMDB000398NADHMetaboCard
PAMDB000424Tetrahydrofolic acidMetaboCard
GO Classification:
Component
glycine cleavage complex
intracellular membrane-bounded organelle
macromolecular complex
membrane-bounded organelle
mitochondrion
organelle
protein complex
Process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
cellular metabolic process
glycine catabolic process
glycine decarboxylation via glycine cleavage system
glycine metabolic process
metabolic process
serine family amino acid metabolic process
Gene Properties
Locus tag: PA5214
Strand: -
Entrez Gene ID: 880637
Accession: NP_253901.1
GI: 15600407
Sequence start: 5871231
Sequence End: 5871620
Sequence Length: 389
Gene Sequence: 
>PA5214
ATGAGCAATATTCCCGCCGAACTGCGTTACGCCCAGAGCCACGAATGGGCTCGCCTGGAAGCCGACGGCAGCGTTACCGTGGGCATTTCCGACCATGCCCAGGAAGCCCTTGGCGATGTGGTCTTCATCGAGCTGCCGGAGCTGGGCAAGACCCTCGCCGCCGGGCAGGAAGCGGGCGTGGTCGAGTCGGTGAAGGCCGCCTCCGACATCTATTCGCCGATCGGCGGCGAAGTCATCGCCATCAACGAAGCCCTGGCCGACACCCCGGAAGACGTCAACAACGACCCGTACGTGTCCTGGTTCTTCAAGCTCAAGCCGAGCAATCCGGCCGAGCTGGACAAGCTGCTCGATGCCGCTGGCTACCAGGCCGCCGTCGACGCGGAAGGCTGA
Protein Properties
Protein Residues: 129
Protein Molecular Weight: 13.6 kDa
Protein Theoretical pI: 3.85
Hydropathicity (GRAVY score): -0.098
Charge at pH 7 (predicted): -15.52
Protein Sequence: 
>PA5214
MSNIPAELRYAQSHEWARLEADGSVTVGISDHAQEALGDVVFIELPELGKTLAAGQEAGVVESVKAASDIYSPIGGEVIAINEALADTPEDVNNDPYVSWFFKLKPSNPAELDKLLDAAGYQAAVDAEG
References
External Links:
Resource Link
Genome ID: PA5214
Entrez Gene ID: 880637
NCBI Protein ID: 15600407
General Reference: PaperBLAST - Find papers about PA5214 and its homologs