Identification
Name: Aerobic respiration control sensor protein ArcB
Synonyms: Not Available
Gene Name: arcB
Enzyme Class:
Biological Properties
General Function: Signal transduction mechanisms
Specific Function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and Asp-576
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+protein L-histidineThumb+protein N-phospho-L-histidine
Adenosine triphosphate + protein L-histidine → ADP + protein N-phospho-L-histidine
ReactionCard
PAMDB110660+PAMDB110083PAMDB001633+PAMDB000198+PAMDB110244
Complex Reactions:
Thumb+protein L-histidineThumb+protein N-phospho-L-histidine
Adenosine triphosphate + protein L-histidine → ADP + protein N-phospho-L-histidine
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
GO Classification:
Component
cell part
integral to membrane
intrinsic to membrane
membrane
membrane part
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
binding
catalytic activity
kinase activity
molecular transducer activity
nucleoside binding
protein histidine kinase activity
protein kinase activity
purine nucleoside binding
signal transducer activity
transferase activity
transferase activity, transferring phosphorus-containing groups
two-component response regulator activity
two-component sensor activity
Process
biological regulation
cellular metabolic process
metabolic process
peptidyl-histidine phosphorylation
phosphate metabolic process
phosphorus metabolic process
phosphorylation
protein amino acid phosphorylation
regulation of biological process
regulation of cellular process
regulation of gene expression
regulation of macromolecule metabolic process
regulation of metabolic process
regulation of transcription
regulation of transcription, DNA-dependent
signal transduction
signal transmission
signaling process
two-component signal transduction system (phosphorelay)
Gene Properties
Locus tag: PA5172
Strand: +
Entrez Gene ID: 881792
Accession: NP_253859.1
GI: 15600365
Sequence start: 5823716
Sequence End: 5824726
Sequence Length: 1010
Gene Sequence:
>PA5172
ATGGCTTTCAACATGCACAACCGTAACCTGCTCAGCCTGATGCACCACAGCACCCGCGAGCTGCGTTACCTGCTCGACCTGTCCCGCGACCTCAAGCGCGCCAAGTACACCGGCACCGAGCAGCAGCACCTGAAGCGCAAGAACATTGCCCTGATCTTCGAGAAAACCTCCACTCGCACCCGCTGCGCCTTCGAGGTGGCCGCCTACGACCAGGGCGCCAACGTCACCTACATCGACCCGAACTCCTCGCAGATCGGCCACAAGGAGAGCATGAAGGACACCGCGCGGGTTCTCGGCCGGATGTACGACGCCATCGAGTACCGCGGCTTCAAGCAGGAAATCGTCGAGGAACTCGCGAAGTTCGCCGGCGTTCCGGTGTTCAACGGCCTGACCGACGAATACCACCCGACCCAGATGCTCGCCGACGTGCTGACCATGCGCGAGCACAGCGACAAGCCGCTGCACGACATCAGCTACGCCTACCTGGGCGACGCGCGCAACAACATGGGCAACTCCCTGCTGCTGATCGGCGCCAAGCTCGGCATGGACGTACGCATCGCCGCACCGAAGGCGCTCTGGCCGCACGACGAGTTCGTCGCCCAGTGCAAGAAGTTCGCCGAGGAAAGCGGCGCCAAGCTGACCCTCACCGAGGATCCGAAGGAAGCCGTGAAGGGCGTGGACTTCGTCCACACCGACGTCTGGGTGTCGATGGGCGAGCCGGTGGAAGCCTGGGGCGAGCGGATCAAGGAACTGCTGCCCTACCAGGTCAACATGGAGATCATGAAGGCCACCGGCAACCCGCGGGCCAAGTTCATGCACTGCCTGCCGGCGTTCCACAACAGCGAGACCAAGGTCGGCAAGCAGATCGCCGAGCAGTATCCGAACCTGGCCAACGGCATCGAGGTGACCGAGGACGTCTTCGAGTCGCCCTACAACATCGCCTTCGAGCAGGCCGAGAACCGCATGCATACCATCAAGGCGATCCTCGTCTCGACCCTCGCCGACATCTGA
Protein Properties
Protein Residues: 336
Protein Molecular Weight: 38.1 kDa
Protein Theoretical pI: 6.58
Hydropathicity (GRAVY score): -0.404
Charge at pH 7 (predicted): -2.96
Protein Sequence:
>PA5172
MAFNMHNRNLLSLMHHSTRELRYLLDLSRDLKRAKYTGTEQQHLKRKNIALIFEKTSTRTRCAFEVAAYDQGANVTYIDPNSSQIGHKESMKDTARVLGRMYDAIEYRGFKQEIVEELAKFAGVPVFNGLTDEYHPTQMLADVLTMREHSDKPLHDISYAYLGDARNNMGNSLLLIGAKLGMDVRIAAPKALWPHDEFVAQCKKFAEESGAKLTLTEDPKEAVKGVDFVHTDVWVSMGEPVEAWGERIKELLPYQVNMEIMKATGNPRAKFMHCLPAFHNSETKVGKQIAEQYPNLANGIEVTEDVFESPYNIAFEQAENRMHTIKAILVSTLADI
References
External Links:
Resource Link
Genome ID: PA5172
Entrez Gene ID: 881792
NCBI Protein ID: 15600365
General Reference: PaperBLAST - Find papers about PA5172 and its homologs