Shikimate kinase 1 (PA5039)

Identification
Name: Shikimate kinase 1
Synonyms:
  • SK 1
  • Shikimate kinase I
  • SKI
Gene Name: aroK
Enzyme Class:
Biological Properties
General Function: Involved in shikimate kinase activity
Specific Function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Cellular Location: Cytoplasm (Probable)
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Adenosine triphosphate + Shikimic acid ↔ ADP + Hydrogen ion + Shikimate 3-phosphate
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + Shikimic acid ↔ ADP + Shikimate 3-phosphate
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Adenosine triphosphate + Shikimic acid ↔ ADP + Hydrogen ion + Shikimate 3-phosphate
ReactionCard
Thumb+Thumb → Thumb+Thumb+Thumb
Shikimic acid + Adenosine triphosphate → Hydrogen ion + Shikimate 3-phosphate + ADP
ReactionCard
Complex Reactions:
Thumb+Thumb → Thumb+Thumb
Adenosine triphosphate + Shikimic acid → ADP + Shikimate 3-phosphate
ReactionCard
Thumb+Thumb → Thumb+Thumb
Adenosine triphosphate + Shikimic acid → ADP + Shikimate 3-phosphate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001039Shikimate 3-phosphateMetaboCard
PAMDB000477Shikimic acidMetaboCard
GO Classification:
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
binding
catalytic activity
kinase activity
nucleoside binding
purine nucleoside binding
shikimate kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Gene Properties
Locus tag: PA5039
Strand: -
Entrez Gene ID: 880961
Accession: NP_253726.1
GI: 15600232
Sequence start: 5675184
Sequence End: 5675702
Sequence Length: 518
Gene Sequence: 
>PA5039
GTGGTCAACCTGATCCTCGTCGGCCCGATGGGTGCTGGAAAGAGCACCATCGGGCGCCTGCTCGCCAAGGAGCTGCATCTCGCGTTCAAGGACTCCGACAAGGAGATCGAACAGCGGTGCGGCGCGAATATCCCATGGATCTTCGATGTCGAGGGCGAGGTCGGTTTCCGCGAGCGTGAGCAGGCCATGCTCACCGAACTCTGCGCCGCCGACGGCATGGTGATCGCCACCGGCGGCGGGGCGGTGATGCGCGACGGTAACCGCCAGGTGCTGCGCGCCGGTGGCCGGGTTGTGTACCTGCATGCCTCGGTCGAGCACCAGATCGCGCGCACGGCGCGGGACCGCAACCGCCCCTTGTTGCAGAAGCCCAACCCAGGACAGATCCTCCGCGACCTGATGGCGCTGCGCGACCCGCTCTACCGCGAAATCGCCGATGTGGTGGTGGAGACCGACGAAAGGCCGCCGCGCCTGGTCGTCCAGGAAATTCTCGAACGCCTGCGCAAGTTGCCGCCCCGCTGA
Protein Properties
Protein Residues: 172
Protein Molecular Weight: 19.2 kDa
Protein Theoretical pI: 8.75
Hydropathicity (GRAVY score): -0.246
Charge at pH 7 (predicted): 2.66
Protein Sequence: 
>PA5039
MVNLILVGPMGAGKSTIGRLLAKELHLAFKDSDKEIEQRCGANIPWIFDVEGEVGFREREQAMLTELCAADGMVIATGGGAVMRDGNRQVLRAGGRVVYLHASVEHQIARTARDRNRPLLQKPNPGQILRDLMALRDPLYREIADVVVETDERPPRLVVQEILERLRKLPPR
References
External Links:
Resource Link
Genome ID: PA5039
Entrez Gene ID: 880961
NCBI Protein ID: 15600232
General Reference: PaperBLAST - Find papers about PA5039 and its homologs