Replicative DNA helicase (PA4931)

Identification
Name: Replicative DNA helicase
Synonyms: Not Available
Gene Name: dnaB
Enzyme Class:
Biological Properties
General Function: Replication, recombination and repair
Specific Function: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins
Cellular Location: Cytoplasmic
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    PAMDB110477 → PAMDB110479+PAMDB110244
    ATP → ADP + phosphate
    ReactionCard
    Complex Reactions:
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB000148Adenosine triphosphateMetaboCard
    PAMDB000345ADPMetaboCard
    PAMDB001776Inorganic phosphateMetaboCard
    PAMDB000142WaterMetaboCard
    GO Classification:
    Function
    adenyl nucleotide binding
    adenyl ribonucleotide binding
    ATP binding
    binding
    catalytic activity
    DNA binding
    DNA helicase activity
    helicase activity
    hydrolase activity
    hydrolase activity, acting on acid anhydrides
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    nucleic acid binding
    nucleoside binding
    nucleoside-triphosphatase activity
    nucleotide binding
    purine nucleoside binding
    pyrophosphatase activity
    Process
    cellular macromolecule metabolic process
    DNA metabolic process
    DNA replication
    macromolecule metabolic process
    metabolic process
    Gene Properties
    Locus tag: PA4931
    Strand: -
    Entrez Gene ID: 879625
    Accession: NP_253618.1
    GI: 15600124
    Sequence start: 5534162
    Sequence End: 5535556
    Sequence Length: 1394
    Gene Sequence: 
    >PA4931
ATGAACGAGATCACCAGCCCCGAGCAATACGACCTGGAAACCACAGCCCTGAAGGTGCCGCCGCACTCGATCGAGGCCGAGCAGGCCGTGCTGGGTGGCCTGATGCTGGACAACAACGCCTGGGAGCGTGTGTCGGATTCGGTGTCCGACGGCGATTTCTACCGCCATGACCATCGCCTGATCTTCCGCGCCATCTACAAGCTGGCCGAGGCCAACCAGCCGATCGACGTGGTGACCCTCTCCGAGCAGTTGGAGAAGGAAGGACAACTGGCCCAGGTCGGCGGCCTGGCCTATCTCGGCGAACTGGCGAAGAACATTCCCTCGGTCGCCAACATCAAGGCCTACGCGCAGATCATCCGCGAGCGCGCCACCCTGCGCCAACTGATCGGCATCAGCAACGAGATCGCCGACAGCGCCTTCCACCCGGAAGGGCGCGGCGCCAACGAGATCCTCGACGAGGCCGAGCGGAAGATCTTCGAGGTCGCCGAAGCGCGACCGAAGACCGGCGGGCCGGTAGGGATCAGCGATATCCTGGTCAAGACCATCGACCGCATCGACTACCTGTTCAACACCACCGAGGCGCTGACCGGGGTGTCCACCGGTTTCACCGACCTCGACGAGAAGACCAGCGGCCTGCAGCCGGCCGACCTGATCATCGTCGCCGGGCGTCCGTCGATGGGTAAGACCACCTTCGCCATGAACCTGGTCGAGAACGCGGTGATGCGCACCGACAAGGCCGTGTTGGTGTACTCCCTGGAGATGCCCTCCGACTCGATCGTGATGCGTATGCTCTCGTCGCTCGGGCGTATCGACCAGACCAAGGTGCGTTCCGGCAAGCTCGACGACGAGGACTGGCCGCGCCTGACTTCGGCGATCAACCTGCTCAACGACAAGAAGCTGTTCATCGACGATACCGCTGGCATCAGTCCCTCGGAAATGCGCGCGCGGACCCGTCGCCTGGTGCGCGAGCACGGCGACCTGGCGCTGATCATGATCGACTACCTGCAACTGATGCAGATACCCGGCTCCAGCGGCGACAACCGGACCAACGAGATTTCCGAGATTTCCCGCTCGCTGAAGGCCCTGGCGAAGGAATTCAACTGCCCGGTGATTGCCCTGTCGCAGCTCAACCGCTCCCTGGAGCAGCGACCCAACAAGCGCCCGGTGAACTCCGACTTGCGCGAATCCGGGGCGATCGAGCAGGACGCCGACGTGATCATGTTCGTCTACCGCGACGAGGTGTACCACCCGGAGACCGAGTTCAAGGGCGTCGCCGAAATCATCATCGGCAAGCAGCGTAACGGTCCGATCGGTACGGTGCGCCTGGCCTTCATCGGCAAATACACGCGCTTCGAGAACCTTGCCGCCGGCATGTACAACTTCGAGGACGAATGA
    Protein Properties
    Protein Residues: 464
    Protein Molecular Weight: 51.6 kDa
    Protein Theoretical pI: 4.71
    Hydropathicity (GRAVY score): -0.294
    Charge at pH 7 (predicted): -16.55
    Protein Sequence: 
    >PA4931
MNEITSPEQYDLETTALKVPPHSIEAEQAVLGGLMLDNNAWERVSDSVSDGDFYRHDHRLIFRAIYKLAEANQPIDVVTLSEQLEKEGQLAQVGGLAYLGELAKNIPSVANIKAYAQIIRERATLRQLIGISNEIADSAFHPEGRGANEILDEAERKIFEVAEARPKTGGPVGISDILVKTIDRIDYLFNTTEALTGVSTGFTDLDEKTSGLQPADLIIVAGRPSMGKTTFAMNLVENAVMRTDKAVLVYSLEMPSDSIVMRMLSSLGRIDQTKVRSGKLDDEDWPRLTSAINLLNDKKLFIDDTAGISPSEMRARTRRLVREHGDLALIMIDYLQLMQIPGSSGDNRTNEISEISRSLKALAKEFNCPVIALSQLNRSLEQRPNKRPVNSDLRESGAIEQDADVIMFVYRDEVYHPETEFKGVAEIIIGKQRNGPIGTVRLAFIGKYTRFENLAAGMYNFEDE
    References
    External Links:
    Resource Link
    Genome ID: PA4931
    Entrez Gene ID: 879625
    NCBI Protein ID: 15600124
    General Reference: PaperBLAST - Find papers about PA4931 and its homologs