P. aeruginosa Metabolome Database Protein PA4180

Identification

Name:

probable acetolactate synthase large subunit

Synonyms:

Not Available

Gene Name:

Not Available

Enzyme Class:

Not Available

Biological Properties

General Function:

Not Available

Specific Function:

magnesium ion binding, thiamine pyrophosphate binding, catalytic activity

Cellular Location:

Cytoplasmic

KEGG Pathways:

superpathway of branched amino acid biosynthesis BRANCHED-CHAIN-AA-SYN-PWY
L-isoleucine biosynthesis I (from threonine) ILEUSYN-PWY
valine biosynthesis VALSYN-PWY

KEGG Reactions:

Not Available

SMPDB Reactions:

Not Available

PseudoCyc/BioCyc Reactions:

pyruvate + 2-oxobutanoate + H⁺ → (S)-2-aceto-2-hydroxybutanoate + CO₂
ReactionCard

→

Hydrogen ion + pyruvate → (S)-2-acetolactate + Carbon dioxide
ReactionCard

Complex Reactions:

Not Available

Transports:

Not Available

Metabolites:

Not Available

GO Classification:

Function
magnesium ion binding
thiamine pyrophosphate binding
catalytic activity

Gene Properties

Locus tag:

PA4180

Strand:

Entrez Gene ID:

880313

Accession:

NP_252869.1

GI:

15599375

Sequence start:

4676282

Sequence End:

4677925

Sequence Length:

1643

Gene Sequence:

>PA4180
ATGGCCAAGGCAGCCGATGTGGTTGTGCAATGCCTGGAAAACGAGGGCGTGCAGTACGTCTTCGGAATTCCCGGCGAGGAGAATCTCGACCTGCTGGAGTCCCTGCGCAAGTCGCAGATCCGGCTGGTGCTCACCCGCCACGAACAATCGGCCGGCTTCATGGCCGCCACCTATGGGCGCCTCACCGGCAAGACCGGGGTCAGCCTGTCGACCCTCGGCCCAGGCGCCACCAACCTGGTGACCGCCGGCGCCTACGCCTACCTGGGCGGCATGCCGATGCTGATGATCACCGGGCAGAAGCCGATCAAGAAGTCCAAGCAGGGCCGCTTCCAGATCCTCGACGTGGTCGGCATGATGCAGCCGCTGACCAAGTACACCCACCAACTGGCCTCCGCCGACAACATTCCCTCGCGGGTCCGCGAGGCGTTCCGCCTGGCCGAGGAAGAGAAGCCCGGCGCGGTGCACCTGGAGCTGCCGGAGGACATCGCCGCCGAGCAGACCGACAGCCTGCCCATCCCGCCGAGCCTGAGCCGCCGGCCGCTGGCGGAATACAAGGCGATCTGCGCCGCGGTGGAGAAGCTGCGCGCCGCGCGCAGCCCGATCCTGGTGATCGGCGCCGGGGCCAACCGCAAGATGACCGCCAAGGTCCTCAAGCAACTGATCGACAAGACCGGCATTCCCTTCGTCACCACCCAGATGGGCAAGGGCGTGGTCGACGAGCGTCACCCGCGCTTCCTCGGCAACGCCGCGCTGTCCGCCGGCGACTTCGTGCATCGCGCGGTGGAGGCGGCCGACCTGATCGTCAACGTCGGCCACGACGTGATCGAGAAGCCGCCGTTCTTCATGGTTCGCGGCGGTACCGAGGTGATCCACGTGAACTTCCGTTCCGCCGAGGTGGACCCGGTGTATTTCCCGCAGATCGAAGTGGTGGGCGACATCGCCAACGCCATCTGGCAGATCGGCGAGGCGCTGGACGATACCGCGCACTGGGACTTCACCCGCCTGCTGGCGATCCGCGAGGCCAACGAGGCGCAGGTCGCCGAAGGCGCCGACGACCCGCGCTTCCCGCTCTACCCGCAGCGCCTGGTGGCCGACGTGCGCCGGGCGTTGCCGTCGCAGGGAATCGTCGCCCTGGACAACGGCATGTACAAGATCTGGTTCGCCCGCAACTACAAGGCACACATGCCCAACACCGTGCTGCTGGACAACGCCCTCGCCACCATGGGCGCCGGCCTGCCCTCGGCGATGGCCGCGCACCTGGTCTACCCGGACCGGCCGATCGTCGCGGTGTGCGGCGATGGCGGCTTCATGATGAACAGCCAGGAACTGGAAACCGCGGTGCGGCTGAAGATGAACCTGACGGTGATCATCCTGCGCGACAACGGCTACGGGATGATCCGCTGGAAGCAATCGAACATGGGCTTCGCCGACTTCGGGCTGGACTACGGCAACCCGGACTTCGTGCACTACGCCGAGGCCTACGGCGCCCACGGCCACCGGGTCGACAGCGCCGAGGGCTTCCTGCCGCTGCTGGAGCGCTGCCTGGGCACGCCCGGGGTGCATGTGATCGATTGCCCGGTGGATTACTCGGAGAACGACCGCATCCTCAACGTCGAGTTGCGCGAACGCGCCCTGGCGGTCTGA

Protein Properties

Protein Residues:

547

Protein Molecular Weight:

59.8 kDa

Protein Theoretical pI:

6.28

Hydropathicity (GRAVY score):

-0.047

Charge at pH 7 (predicted):

-5.76

Protein Sequence:

>PA4180
MAKAADVVVQCLENEGVQYVFGIPGEENLDLLESLRKSQIRLVLTRHEQSAGFMAATYGRLTGKTGVSLSTLGPGATNLVTAGAYAYLGGMPMLMITGQKPIKKSKQGRFQILDVVGMMQPLTKYTHQLASADNIPSRVREAFRLAEEEKPGAVHLELPEDIAAEQTDSLPIPPSLSRRPLAEYKAICAAVEKLRAARSPILVIGAGANRKMTAKVLKQLIDKTGIPFVTTQMGKGVVDERHPRFLGNAALSAGDFVHRAVEAADLIVNVGHDVIEKPPFFMVRGGTEVIHVNFRSAEVDPVYFPQIEVVGDIANAIWQIGEALDDTAHWDFTRLLAIREANEAQVAEGADDPRFPLYPQRLVADVRRALPSQGIVALDNGMYKIWFARNYKAHMPNTVLLDNALATMGAGLPSAMAAHLVYPDRPIVAVCGDGGFMMNSQELETAVRLKMNLTVIILRDNGYGMIRWKQSNMGFADFGLDYGNPDFVHYAEAYGAHGHRVDSAEGFLPLLERCLGTPGVHVIDCPVDYSENDRILNVELRERALAV

References

External Links:

Resource	Link
Genome ID:	PA4180
Entrez Gene ID:	880313
NCBI Protein ID:	15599375

General Reference:

PaperBLAST - Find papers about PA4180 and its homologs

probable acetolactate synthase large subunit (PA4180)