Identification
Name: thiopurine methyltransferase
Synonyms: Not Available
Gene Name: tpm
Enzyme Class: Not Available
Biological Properties
General Function: nucleotide metabolic process, response to stimulus, methylation, response to metal ion
Specific Function: betaine-aldehyde dehydrogenase activity, S-adenosylmethionine-dependent methyltransferase activity, thiopurine S-methyltransferase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    a thiopurine + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + a thiopurine S-methylether + H+
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    betaine-aldehyde dehydrogenase activity
    S-adenosylmethionine-dependent methyltransferase activity
    thiopurine S-methyltransferase activity
    Process
    nucleotide metabolic process
    response to stimulus
    methylation
    response to metal ion
    Gene Properties
    Locus tag: PA2832
    Strand: -
    Entrez Gene ID: 882816
    Accession: NP_251522.1
    GI: 15598028
    Sequence start: 3185161
    Sequence End: 3185817
    Sequence Length: 656
    Gene Sequence:
    >PA2832
    ATGCAGGCGGATTTTTGGCACGCCCGCTGGGCGAACAACCAGATCGGCTTCCACCTGGACGAGATCAATCCCTACCTGATGCGCCACCTGTCGCGGCTGCGACTGCAAGCGGGCGAACAGATCCTGGTGCCGTTGTGCGGCAAGACCCTGGACCTGGCCTGGCTGGCCGCCCAGGGACTGGAGGTGCTGGGGGTGGAGCTTTCGGAAAAGGCCGTGAGCGACTTCTTCGAGGAGCACGACCTGCACCCCGAGATCGATCAACTGGATGGTTTCCGCCGCTACCGGGTCGCCGGCATCACCCTGCTGCAGGGTGATTTCTTCGCCTTGCAGGCAGAGCACCTGGCGCAGTGCAGGGCGTTCTACGACCGCGCCGCGCTGATCGCCCTGCCGCCGGAGATGCGCGAGCGCTATGCCGGGCATCTCCAGGCGGTCCTGCCGACGCGCAGCCTCGGCTTGCTGGTCACCATCGACTACCCGCAGGCGGAGATGGCCGGTCCGCCGTTCGCCGTGCCCGACGAGGAGGTGCGTGGCTACTACGCTGGCGGTTGGCGGATCGAGGAACTGGAGCGCGGCGACGTGCTCGGCGTCAACTGGAAATTCCTCGAGCGCGGGGTGTCCTGGCTGGACGAGGCCGTCTACCTGCTGGAGAGAGGCTGA
    Protein Properties
    Protein Residues: 218
    Protein Molecular Weight: 24.9 kDa
    Protein Theoretical pI: 4.68
    Hydropathicity (GRAVY score): -0.139
    Charge at pH 7 (predicted): -11.38
    Protein Sequence:
    >PA2832
    MQADFWHARWANNQIGFHLDEINPYLMRHLSRLRLQAGEQILVPLCGKTLDLAWLAAQGLEVLGVELSEKAVSDFFEEHDLHPEIDQLDGFRRYRVAGITLLQGDFFALQAEHLAQCRAFYDRAALIALPPEMRERYAGHLQAVLPTRSLGLLVTIDYPQAEMAGPPFAVPDEEVRGYYAGGWRIEELERGDVLGVNWKFLERGVSWLDEAVYLLERG
    References
    External Links:
    Resource Link
    Genome ID: PA2832
    Entrez Gene ID: 882816
    NCBI Protein ID: 15598028
    General Reference: PaperBLAST - Find papers about PA2832 and its homologs