anthranilate dioxygenase large subunit (PA2512)

Identification
Name: anthranilate dioxygenase large subunit
Synonyms: Not Available
Gene Name: antA
Enzyme Class: Not Available
Biological Properties
General Function: carbon utilization, aromatic compound catabolic process, cellular catabolic process, oxidation-reduction process, cellular aromatic compound metabolic process
Specific Function: iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor, oxidoreductase activity, 2 iron, 2 sulfur cluster binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Cellular Location: Cytoplasmic
KEGG Pathways:
  • anthranilate degradation I (aerobic) PWY-6079
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    PAMDB110108+PAMDB000624+NADH-P-OR-NOP+PAMDB001633 → PAMDB110454+PAMDB000568+PAMDB001595+NAD-P-OR-NOP
    anthranilate + Oxygen + NADH-P-OR-NOP + Hydrogen ion → catechol + Carbon dioxide + Ammonium + NAD-P-OR-NOP
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    iron ion binding
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
    oxidoreductase activity
    2 iron, 2 sulfur cluster binding
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    Process
    carbon utilization
    aromatic compound catabolic process
    cellular catabolic process
    oxidation-reduction process
    cellular aromatic compound metabolic process
    Gene Properties
    Locus tag: PA2512
    Strand: +
    Entrez Gene ID: 882892
    Accession: NP_251202.1
    GI: 15597708
    Sequence start: 2829440
    Sequence End: 2830834
    Sequence Length: 1394
    Gene Sequence: 
    >PA2512
ATGAACGCTACCCGCAGAAGCCTCGAACAGTGGCGCGACTATGTCGGCGGCTGCCTCGACTTCCGTCCCGAGGAAGGCATCTTCCGCATCGCCCGGGACATGTTCACCGAACCGGAGCTGTTCGACCTGGAGATGGAGCTGATCTTCGAAAAGAACTGGATCTACGCCTGCCACGAAAGCGAACTGGCCAGGCCCCACGACTTCGTCACCCTGCGCGCCGGACGCCAGCCGCTGATCGTCACCCGCGACGGCAACGGCCAGTTGCACGCGCTGGTCAACGCCTGCCAGCATCGCGGCGCGACCCTGGTGCGGGTCGGCAAGGGCAACCAGTCGACCTTCACCTGTCCGTTCCATGCCTGGTGCTACAAGAACGACGGCCGGCTGGTGAAGGTCAAGGCGCCGGGCGAATACCCGGAAGGCTTCGACAAGGCCACCCGTGGCCTGAAGAAAGCGCGCATCCAGAGCTACAGGGGCTTCGTCTTCGTCAGCCTGGACGTCGCCGGCGAGGACGACCTGGTGGACTTCCTCGGCGACGCCCGGGTGTTCCTCGACATGCTGGTGGCGCAGTCTCCCAGCGGCGAGCTGGAAGTGTTGCCCGGCACCTCCACCTACACCTACGAAGGCAACTGGAAGCTGCAGAACGAGAATGGCCTGGACGGCTATCACGTCAGCACAGTGCACTACAACTACGTAGCCACCGTGCAGCACCGCCAGCAGGTCGAGGCCGAGCGCGGCGGCGTGGCCGCCACCCTCGACTACAGCAAGCTCGGCGCCGGCGACGCGGCCACCGACGACGGCTGGTTCTCCTTCGCCAACGGCCACAGCGTGCTCTTCAGCGAGATGCCCAACCCCGCCGTACGCCCCGGCTACGCCAGCGTGATGCCGCGGCTGGTGGCGGAATACGGCCAGGCCCGCGCCGAGTGGATGATGCATCGCCTGCGCAACCTCAATCTCTACCCCAGCCTGTTCGTCATCGACCAGATCAGCTCGCAGCTGCGCATCGTCCGCCCGCTGGCCTGGAACCGTACCGAGATCGTCAGCCAGTGCATCGGCGTCAAGGGCGAGTCGGACGCCGACCGGGAGAACCGGATCCGCCAGTTCGAGGACTTCTTCAACGTCTCCGGGATGGGCACGCCCGACGACCTGGTGGAGTTCCGCGAAGCCCAGCGTGGCTTCCAGGCCCGCCTGGAGCGCTGGAGCGACATCTCCCGCGGCCACGGCAAGTGGCTCGAAGGCGCGACGCCGAACAGCCAGGCGCTGGGTATCGCGCCGCTGCTGACCGGCACCGAGATCACCCACGAAGGCCTCTACGTCAACCAGCACGCGCATTGGCGGCGCTTCCTCCTCGACGGCCTGGAGCGCCTGGCCCTGCGCGCGAAGGAGGTGACCCCATGA
    Protein Properties
    Protein Residues: 464
    Protein Molecular Weight: 52.5 kDa
    Protein Theoretical pI: 6.28
    Hydropathicity (GRAVY score): -0.414
    Charge at pH 7 (predicted): -5.79
    Protein Sequence: 
    >PA2512
MNATRRSLEQWRDYVGGCLDFRPEEGIFRIARDMFTEPELFDLEMELIFEKNWIYACHESELARPHDFVTLRAGRQPLIVTRDGNGQLHALVNACQHRGATLVRVGKGNQSTFTCPFHAWCYKNDGRLVKVKAPGEYPEGFDKATRGLKKARIQSYRGFVFVSLDVAGEDDLVDFLGDARVFLDMLVAQSPSGELEVLPGTSTYTYEGNWKLQNENGLDGYHVSTVHYNYVATVQHRQQVEAERGGVAATLDYSKLGAGDAATDDGWFSFANGHSVLFSEMPNPAVRPGYASVMPRLVAEYGQARAEWMMHRLRNLNLYPSLFVIDQISSQLRIVRPLAWNRTEIVSQCIGVKGESDADRENRIRQFEDFFNVSGMGTPDDLVEFREAQRGFQARLERWSDISRGHGKWLEGATPNSQALGIAPLLTGTEITHEGLYVNQHAHWRRFLLDGLERLALRAKEVTP
    References
    External Links:
    Resource Link
    Genome ID: PA2512
    Entrez Gene ID: 882892
    NCBI Protein ID: 15597708
    General Reference: PaperBLAST - Find papers about PA2512 and its homologs