L-asparaginase 1 (PA2253)

Identification
Name: L-asparaginase 1
Synonyms:
  • L-asparaginase I
  • L-ASNase I
  • L-asparagine amidohydrolase I
Gene Name: ansA
Enzyme Class:
Biological Properties
General Function: Involved in asparaginase activity
Specific Function: L-asparagine + H(2)O = L-aspartate + NH(3)
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb
L-Asparagine + Water ↔ L-Aspartic acid + Ammonia
ReactionCard
Thumb+Thumb → Thumb+Thumb+Thumb
L-Asparagine + Water → Hydrogen ion + L-Aspartic acid + Ammonia
ReactionCard
SMPDB Reactions:
L-Asparagine+Thumb+Thumb → L-Aspartic acid+Thumb+Thumb
L-Asparagine + Water + L-Asparagine → L-Aspartic acid + Ammonium + L-Aspartic acid
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb → Thumb+Thumb+Thumb
L-Asparagine + Water → Hydrogen ion + L-Aspartic acid + Ammonia
ReactionCard
Complex Reactions:
Thumb+Thumb → Thumb+Thumb
L-Asparagine + Water → L-Aspartic acid + Ammonium
ReactionCard
Thumb+Thumb → Thumb+Thumb
L-Asparagine + Water → L-Aspartic acid + Ammonia
ReactionCard
Thumb+Thumb → Thumb+Thumb
L-Asparagine + Water → L-Aspartic acid + Ammonia
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000017AmmoniaMetaboCard
PAMDB001595AmmoniumMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000069L-AsparagineMetaboCard
PAMDB000080L-Aspartic acidMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
asparaginase activity
catalytic activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
cellular metabolic process
metabolic process
Gene Properties
Locus tag: PA2253
Strand: +
Entrez Gene ID: 878133
Accession: NP_250943.1
GI: 15597449
Sequence start: 2480844
Sequence End: 2481830
Sequence Length: 986
Gene Sequence: 
>PA2253
ATGCTCCCAGTCAAGAACCTCTTCGTGCTCTACACCGGCGGCACCATCGGCATGTTGCAGACCCCGCAGGGACTGGCTCCGGCCGGTGGCTTCGAAGCGCGCATGCGCGACCACCTGCAAAGCCTCGGCGACGCCCCGGACCTGCGCTGGCGCTTCGCCGAACTGCAACCGCCGCTGGACAGCGCCAACATGACCCAGGGCAACTGGCTGGCGATGCGCGACGCCATCGTCGCCGCGCTCGACGCCGGCCACGACGGCGTGCTGCTCCTGCACGGCACCGACACCCTGGCCTACAGCGCCGCGGCGCTGTCCTTCCTGCTCCTCGACCTGCCGATCCCGGTGCTGCTGACCGGCTCCATGCTGCCGGCCGGCGCGCCGGGCAGCGATGCCTGGGACAACCTGGTCGGCGCCCTGCGCGTCCTCCAGGAGGGCCACGCGCGCGGCGTACAGGTCTATTTCAACGATGCCCTGCTGCACGGCGCGCGAGTCAGCAAGCTGCGCAGCGACGCGTTCGACGCCTTCGCCGAACTGCCGCGACCGCGCCACGCCGAGCATGCGCCGGTGCCTGCGGCGCTCGGCTACCGCCAGCCGCGCCGGGAAGTGAACCTCGCCGTGCTGCCGCTCTATCCAGGGCTGCGCGCCGCGCACCTGCGCGGGCTGCTCGACAGCGGCGTGGAAGCGCTGCTGCTGGAATGCTATGGCAGCGGCACCGGCCCGTCCGACGACGAGGAGCTGCTGGCGCTGCTGCGCGAAGCCCACGCCCGCGGCGTGCTGCTCGCCGCGGTCAGCCAGTGCGCCTACGGCCAGGTCGAGTTCGGCGTCTACGCCGCCGGCAGCCGCCTGCGCGACGCCGGCCTGCTCTCGGCTGGCGGAATGACCCGCGAGGCGGCCCTGGGCAAGCTCTTCGGCCTGCTCGGCGCCGGCCTCGGACGCGACGAAGCGCAACGCTGGTTCGCCCTCGACCTGTGCGGCGAGAACGCCGACTGA
Protein Properties
Protein Residues: 328
Protein Molecular Weight: 34.8 kDa
Protein Theoretical pI: 5.34
Hydropathicity (GRAVY score): 0.116
Charge at pH 7 (predicted): -7.93
Protein Sequence: 
>PA2253
MLPVKNLFVLYTGGTIGMLQTPQGLAPAGGFEARMRDHLQSLGDAPDLRWRFAELQPPLDSANMTQGNWLAMRDAIVAALDAGHDGVLLLHGTDTLAYSAAALSFLLLDLPIPVLLTGSMLPAGAPGSDAWDNLVGALRVLQEGHARGVQVYFNDALLHGARVSKLRSDAFDAFAELPRPRHAEHAPVPAALGYRQPRREVNLAVLPLYPGLRAAHLRGLLDSGVEALLLECYGSGTGPSDDEELLALLREAHARGVLLAAVSQCAYGQVEFGVYAAGSRLRDAGLLSAGGMTREAALGKLFGLLGAGLGRDEAQRWFALDLCGENAD
References
External Links:
Resource Link
Genome ID: PA2253
Entrez Gene ID: 878133
NCBI Protein ID: 15597449
General Reference: PaperBLAST - Find papers about PA2253 and its homologs