Identification
Name: Murein tetrapeptide carboxypeptidase
Synonyms:
  • LD-carboxypeptidase A
  • Muramoyltetrapeptide carboxypeptidase
Gene Name: ldcA
Enzyme Class:
Biological Properties
General Function: cellular amino acid metabolic process
Specific Function: catalytic activity, carboxy-lyase activity, pyridoxal phosphate binding
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions:
Thumb+ThumbThumb+Thumb
PseudoCyc/BioCyc Reactions:
Thumb+ThumbThumb+Thumb
Complex Reactions:
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
Thumb+ThumbGlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate+Thumb
GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanine + Water → GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate + D-Alanine
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0015201,6-Anhydrous-N-Acetylmuramyl-tetrapeptideMetaboCard
PAMDB0015211,6-Anhydrous-N-Acetylmuramyl-tripeptideMetaboCard
PAMDB000333D-AlanineMetaboCard
PAMDB003536GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanineMetaboCard
PAMDB001378L-Ala-gamma-D-Glu-DapMetaboCard
PAMDB000063L-AlanineMetaboCard
PAMDB001648L-alanine-D-glutamate-meso-2,6-diaminoheptanedioateMetaboCard
PAMDB001647L-Alanine-D-glutamate-meso-2,6-diaminoheptanedioate-D-alanineMetaboCard
PAMDB001657N-Acetyl-D-glucosamine(anhydrous)N-Acetylmuramyl-tetrapeptideMetaboCard
PAMDB001658N-Acetyl-D-glucosamine(anhydrous)N-Acetylmuramyl-tripeptideMetaboCard
PAMDB000650UDP-N-Acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioateMetaboCard
PAMDB001419UDP-N-Acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate-D-alanineMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Component
cytoplasm
Function
catalytic activity
carboxy-lyase activity
pyridoxal phosphate binding
Process
cellular amino acid metabolic process
Gene Properties
Locus tag: PA1818
Strand: +
Entrez Gene ID: 878596
Accession: NP_250509.1
GI: 15597015
Sequence start: 1974821
Sequence End: 1977076
Sequence Length: 2255
Gene Sequence:
>PA1818
ATGTATAAAGACCTCAAATTTCCCGTCCTCATCGTCCATCGCGACATCAAGGCCGACACCGTTGCCGGCGAACGCGTGCGGGGCATCGCCCACGAACTGGAGCAGGACGGCTTCAGCATTCTCTCCACCGCCAGCTCCGCCGAGGGGCGCATCGTCGCTTCCACCCACCACGGCCTGGCCTGCATTCTGGTCGCCGCCGAAGGTGCCGGGGAAAACCAGCGCCTGCTGCAGGATGTGGTCGAACTGATCCGCGTGGCCCGCGTGCGGGCGCCGCAATTGCCGATCTTCGCCCTCGGCGAGCAGGTGACCATCGAGAACGCGCCGGCCGAGTCCATGGCCGACCTGCACCAGTTGCGCGGCATCCTCTACCTGTTCGAAGACACCGTGCCGTTCCTCGCCCGCCAGGTCGCCCGGGCGGCGCGCAACTACCTGGCCGGGCTGCTGCCGCCATTCTTCCGTGCGCTGGTCGAGCACACCGCGCAGTCCAACTATTCCTGGCATACGCCGGGCCACGGCGGCGGTGTCGCCTATCGCAAGAGTCCGGTGGGACAGGCGTTCCACCAGTTCTTCGGGGAGAACACGCTGCGTTCCGACCTGTCGGTCTCGGTCCCCGAGCTGGGATCGCTGCTCGACCATACCGGCCCCCTGGCCGAGGCCGAGGACCGTGCCGCGCGCAATTTCGGCGCCGACCATACCTTCTTCGTGATCAATGGCACTTCCACCGCGAACAAGATCGTCTGGCACTCCATGGTCGGTCGCGAAGACCTGGTGCTGGTGGACCGCAACTGCCACAAGTCGATCCTCCACTCGATCATCATGACCGGGGCGATACCGCTCTACCTGACTCCGGAACGCAACGAACTGGGGATCATCGGGCCGATCCCGCTGAGCGAATTCAGCAAGCAGTCGATCGCCGCGAAGATCGCCGCCAGCCCGCTGGCGCGCGGCCGCGAGCCGAAGGTGAAGCTGGCGGTGGTGACTAACTCCACCTACGACGGCCTGTGCTACAACGCCGAGCTGATCAAGCAGACCCTCGGCGACAGCGTCGAGGTGTTGCACTTCGACGAGGCTTGGTACGCCTATGCCGCGTTCCACGAGTTCTACGACGGACGCTATGGCATGGGCACCTCGCGCAGCGAGGAGGGACCCCTGGTGTTCGCCACCCACTCCACGCACAAGATGCTCGCCGCCTTCAGCCAGGCCTCGATGATCCACGTGCAGGATGGCGGGACCCGGAAGCTGGACGTGGCGCGCTTCAACGAAGCCTTCATGATGCACATCTCGACCTCGCCGCAGTACGGCATCATCGCTTCGCTGGACGTGGCTTCGGCGATGATGGAAGGGCCCGCCGGGCGTTCGCTGATCCAGGAGACCTTCGACGAGGCCCTCAGCTTCCGCCGGGCCCTGGCCAACGTACGGCAGAACCTGGACCGGAACGACTGGTGGTTCGGCGTCTGGCAGCCGGAGCAGGTGGAGGGCACCGACCAGGTCGGCACCCATGACTGGGTGCTGGAGCCGAGCGCCGACTGGCACGGCTTCGGCGATATCGCCGAAGACTACGTGCTGCTCGACCCGATCAAGGTCACCCTGACCACCCCGGGCCTGAGCGCTGGCGGCAAGCTCAGCGAGCAGGGGATTCCGGCCGCCATCGTCAGCCGCTTCCTCTGGGAGCGCGGGCTGGTGGTGGAGAAAACCGGTCTCTACTCCTTCCTGGTGCTGTTCTCGATGGGCATCACCAAGGGCAAGTGGAGCACCCTGGTCACCGAACTGCTCGAATTCAAGCGCTGTTACGACGCCAACCTGCCGCTGCTTGACGTCTTGCCCTCCGTGGCCCAGGCCGGCGGCAAGCGCTACAACGGAGTGGGCCTGCGCGACCTCAGCGACGCCATGCACGCCAGCTACCGCGACAACGCCACGGCGAAGGCCATGAAGCGCATGTACACGGTGCTGCCGGAGGTCGCGATGCGGCCGTCCGAGGCCTACGACAAGCTGGTGCGCGGCGAGGTCGAGGCGGTACCGATCGCTCGGTTGGAAGGGCGCATCGCGGCCGTCATGCTGGTACCCTATCCGCCGGGTATCCCGCTGATCATGCCGGGTGAGCGCTTCACCGAGGCGACCCGCTCGATCCTCGACTATCTCGAGTTCGCGCGGACCTTCGAGCGCGCCTTCCCTGGTTTCGACTCCGATGTGCATGGCCTGCAGCATCAGGACGGACCGTCCGGGCGCTGCTATACCGTTGAATGCATAAAGGAATGA
Protein Properties
Protein Residues: 751
Protein Molecular Weight: 82.8 kDa
Protein Theoretical pI: 6.07
Hydropathicity (GRAVY score): -0.083
Charge at pH 7 (predicted): -13.13
Protein Sequence:
>PA1818
MYKDLKFPVLIVHRDIKADTVAGERVRGIAHELEQDGFSILSTASSAEGRIVASTHHGLACILVAAEGAGENQRLLQDVVELIRVARVRAPQLPIFALGEQVTIENAPAESMADLHQLRGILYLFEDTVPFLARQVARAARNYLAGLLPPFFRALVEHTAQSNYSWHTPGHGGGVAYRKSPVGQAFHQFFGENTLRSDLSVSVPELGSLLDHTGPLAEAEDRAARNFGADHTFFVINGTSTANKIVWHSMVGREDLVLVDRNCHKSILHSIIMTGAIPLYLTPERNELGIIGPIPLSEFSKQSIAAKIAASPLARGREPKVKLAVVTNSTYDGLCYNAELIKQTLGDSVEVLHFDEAWYAYAAFHEFYDGRYGMGTSRSEEGPLVFATHSTHKMLAAFSQASMIHVQDGGTRKLDVARFNEAFMMHISTSPQYGIIASLDVASAMMEGPAGRSLIQETFDEALSFRRALANVRQNLDRNDWWFGVWQPEQVEGTDQVGTHDWVLEPSADWHGFGDIAEDYVLLDPIKVTLTTPGLSAGGKLSEQGIPAAIVSRFLWERGLVVEKTGLYSFLVLFSMGITKGKWSTLVTELLEFKRCYDANLPLLDVLPSVAQAGGKRYNGVGLRDLSDAMHASYRDNATAKAMKRMYTVLPEVAMRPSEAYDKLVRGEVEAVPIARLEGRIAAVMLVPYPPGIPLIMPGERFTEATRSILDYLEFARTFERAFPGFDSDVHGLQHQDGPSGRCYTVECIKE
References
External Links:
Resource Link
Genome ID: PA1818
Entrez Gene ID: 878596
NCBI Protein ID: 15597015
General Reference: PaperBLAST - Find papers about PA1818 and its homologs