Identification
Name: Aconitate hydratase 2
Synonyms:
  • Aconitase
  • Citrate hydro-lyase
Gene Name: acnB
Enzyme Class:
Biological Properties
General Function: Involved in metabolic process
Specific Function: Citrate = isocitrate
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
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ThumbThumb+Thumb
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ThumbThumb
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SMPDB Reactions:
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PseudoCyc/BioCyc Reactions:
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Complex Reactions:
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000668Cis-2-MethylaconitateMetaboCard
PAMDB000025cis-Aconitic acidMetaboCard
PAMDB000034Citric acidMetaboCard
PAMDB006191D-threo-Isocitric acidMetaboCard
PAMDB000604Isocitric acidMetaboCard
PAMDB000674Methylisocitric acidMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
4 iron, 4 sulfur cluster binding
aconitate hydratase activity
binding
carbon-oxygen lyase activity
catalytic activity
hydro-lyase activity
iron-sulfur cluster binding
lyase activity
metal cluster binding
protein binding
Process
acetyl-CoA catabolic process
acetyl-CoA metabolic process
cellular metabolic process
coenzyme metabolic process
cofactor metabolic process
metabolic process
tricarboxylic acid cycle
Gene Properties
Locus tag: PA1787
Strand: -
Entrez Gene ID: 879984
Accession: NP_250478.1
GI: 15596984
Sequence start: 1935035
Sequence End: 1937644
Sequence Length: 2609
Gene Sequence:
>PA1787
GTGCTTGAAGCCTACCGCAAACACGTAGAAGAGCGTGCCGCCCAGGGTGTCGTGCCCCAACCGCTGAACGCCGAACAGACCGCAGGCCTGGTCGAGCTGCTGAAGAACCCGCCGGCCGGCGAAGAAGAATTCCTCCTTGACCTGATCACCAACCGCGTACCGCCGGGCGTCGACGAAGCCGCCTACGTCAAGGCCGGATTCCTTTCCGCCATCGTCAAGGGCGAAGCCACCTCCCCCCTTATCGACAAGCAACGTGCCGCCGAGCTGCTGGGCACCATGCAGGGCGGCTACAACATCGCCACCCTGGTCGAACTGCTGGACGACGCCGAACTGGCCAACACCGCCGCCGAACAGCTGAAGCACACCCTGCTGATGTTCGACGCCTTCCACGACGTCGCCGAGCGCGCCAAGAAGGGCAATGCCGCGGCCAAGTCCGTGCTGCAATCCTGGGCCGATGGCGAGTGGTTCAAGGCCAAGCCGGAAGTCCCGGAAAAGCTGACTCTCACCGTATTCAAGGTCCCCGGCGAAACCAACACCGACGACCTCTCCCCGGCCCCCGACGCCTGGTCGCGCCCGGACATCCCGCTGCACGCCCTGGCCATGCTGAAGATGGCCCGCGACGGCATCGAGCCGGTCCAGCCGGGTTCGGTCGGTCCGCTGAAGCAGATCGAAGCGGTCAAGGCCAAGGGCTTCCCGGTCGCCTACGTCGGCGACGTGGTCGGCACCGGTTCCTCGCGCAAATCCGCCACCAACTCGGTGCTGTGGTTCTTCGGCGACGACATTCCGTTCGTGCCGAACAAGCGTGCCGGCGGCTTCTGCTTCGGCACCAAGATCGCACCGATCTTCTACAACACCATGGAAGATGCCGGCGCCCTGCCGATCGAGTTCGACTGCACCAACCTGGCCATGGGCGACGTCATCGACGTATACCCCTATGAAGGCAAGGTCGTTCGCCACGACAGCGGCGAAGTGGTCACCACCTTCGAGCTGAAGACCCCGGTCCTGCTCGACGAAGTCCGCGCCGGCGGCCGTATCCCGCTGATCGTCGGCCGTGGCCTGACCGAGAAGGCCCGCGCCGAGCTGGGCCTGGGCGCCTCCGACCTGTTCCGCAAGCCGGAAGCACCGGCCGATAGCGGCAAGGGCTTCACCCTGGCGCAGAAAATGGTCGGCCGCGCCTGCGGTCTGCCGGAAGGCCAGGGCGTGCGCCCGGGCACCTACTGCGAACCGAAGATGACCACCGTCGGTTCCCAGGACACCACCGGCCCGATGACCCGCGACGAACTGAAGGACCTCGCCTGCCTCGGCTTCTCCGCCGACCTGGTGATGCAGTCCTTCTGCCACACCGCGGCCTATCCGAAGCCGATCGACGTCAAGACCCACCACACCCTGCCCGACTTCATCATGACCCGTGGCGGCGTGTCGCTGCGTCCGGGCGACGGCATCATCCACAGCTGGCTGAACCGCATGCTGCTGCCCGATACCGTTGGTACCGGCGGCGACTCGCACACCCGCTTCCCGATCGGCATCTCGTTCCCGGCCGGCTCCGGCCTGGTGGCCTTCGCCGCCGCCACCGGCGTGATGCCGCTGGACATGCCGGAGTCGGTGCTGGTGCGCTTCAAGGGCAAGCTGCAACCGGGCATCACCCTGCGTGACCTGGTCCATGCGATCCCTTACTACGCGATCCAGCAGGGCCTGCTGACCGTCGAGAAGAAGGGCAAGAAGAACATCTTCTCCGGCCGCATCCTCGAGATCGAAGGCCTCAACGACCTGACCGTGGAGCAGGCCTTCGAGCTGTCCGACGCCTCGGCCGAGCGTTCCGCCGCCGGCTGCACCATCAAGCTGCCGGAACAGGCGATCGCCGAGTACCTGAAGTCCAACATCACCCTGCTGCGCTGGATGATCGGCGAAGGCTACGGCGACCCGCGCACCCTGGAGCGTCGCGCCCAGGCGATGGAAGCCTGGCTGGCCAAGCCGGAGCTGCTGGAAGCCGACAAGGACGCCGAGTACGCCGCGGTGATCGAGATCGACCTGGCCGACGTCAAGGAGCCAGTGCTCTGCGCGCCGAACGATCCGGACGACGCGCGTCTGCTGTCGAGCGTACAGGGCCGCAAGATCGATGAAGTGTTCATCGGCTCCTGCATGACCAACATCGGTCACTTCCGCGCCGCCGGCAAGCTGCTGGACAAGGTCAAGGGCGGCATCCCGACCCGTCTGTGGCTGGCTCCGCCGACCAAGATGGACGCCCACCAGCTGACCGAGGAAGGCTACTACGGCATCTACGGCAAGGCTGGCGCGCGCATGGAAATGCCGGGCTGCTCGCTGTGCATGGGCAACCAGGCTCGCGTCCAGACCGGTTCCACCGTGGTCTCCACTTCGACCCGTAACTTCCCGAACCGTCTGGGCGATGCCACCGATGTGTTCCTGGCATCGGCCGAGCTGGCGGCGGTCTCCTCGATCCTCGGCAAACTGCCGACCGTGGAGGAGTACATGGCCTACGCGAAGGACATCGACAGCATGGCTGCCGACGTCTACCGCTACCTGAGCTTCGACCAGATCGCCGAGTTCCGCGAAGCGGCTGCGAACGCCAAGATCCCGGTCGTCCAGGCCTGA
Protein Properties
Protein Residues: 869
Protein Molecular Weight: 93.6 kDa
Protein Theoretical pI: 5.01
Hydropathicity (GRAVY score): -0.101
Charge at pH 7 (predicted): -20.15
Protein Sequence:
>PA1787
MLEAYRKHVEERAAQGVVPQPLNAEQTAGLVELLKNPPAGEEEFLLDLITNRVPPGVDEAAYVKAGFLSAIVKGEATSPLIDKQRAAELLGTMQGGYNIATLVELLDDAELANTAAEQLKHTLLMFDAFHDVAERAKKGNAAAKSVLQSWADGEWFKAKPEVPEKLTLTVFKVPGETNTDDLSPAPDAWSRPDIPLHALAMLKMARDGIEPVQPGSVGPLKQIEAVKAKGFPVAYVGDVVGTGSSRKSATNSVLWFFGDDIPFVPNKRAGGFCFGTKIAPIFYNTMEDAGALPIEFDCTNLAMGDVIDVYPYEGKVVRHDSGEVVTTFELKTPVLLDEVRAGGRIPLIVGRGLTEKARAELGLGASDLFRKPEAPADSGKGFTLAQKMVGRACGLPEGQGVRPGTYCEPKMTTVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPIDVKTHHTLPDFIMTRGGVSLRPGDGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKLQPGITLRDLVHAIPYYAIQQGLLTVEKKGKKNIFSGRILEIEGLNDLTVEQAFELSDASAERSAAGCTIKLPEQAIAEYLKSNITLLRWMIGEGYGDPRTLERRAQAMEAWLAKPELLEADKDAEYAAVIEIDLADVKEPVLCAPNDPDDARLLSSVQGRKIDEVFIGSCMTNIGHFRAAGKLLDKVKGGIPTRLWLAPPTKMDAHQLTEEGYYGIYGKAGARMEMPGCSLCMGNQARVQTGSTVVSTSTRNFPNRLGDATDVFLASAELAAVSSILGKLPTVEEYMAYAKDIDSMAADVYRYLSFDQIAEFREAAANAKIPVVQA
References
External Links:
Resource Link
Genome ID: PA1787
Entrez Gene ID: 879984
NCBI Protein ID: 15596984
General Reference: PaperBLAST - Find papers about PA1787 and its homologs