uroporphyrin-III C-methyltransferase S-adenosyl-L-methionine:uroporphyrinogen III (PA1778)

Identification
Name: uroporphyrin-III C-methyltransferase S-adenosyl-L-methionine:uroporphyrinogen III
Synonyms: Not Available
Gene Name: cobA
Enzyme Class: Not Available
Biological Properties
General Function: chlorophyll metabolic process, cofactor biosynthetic process, oxidation-reduction process, porphyrin-containing compound biosynthetic process, metabolic process
Specific Function: precorrin-2 dehydrogenase activity, methyltransferase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
  • adenosylcobalamin biosynthesis II (late cobalt incorporation) P381-PWY
  • cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation) PWY-7376
  • cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion) PWY-7377
  • siroheme biosynthesis PWY-5194
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    S-adenosyl-L-methionine + uroporphyrinogen-III → S-adenosyl-L-homocysteine + precorrin-1 + H+
    ReactionCard
    PAMDB000289+PAMDB110805 → PAMDB000205+PAMDB110719+PAMDB001633
    S-Adenosylmethionine + uroporphyrinogen-III → S-Adenosylhomocysteine + precorrin-2 + Hydrogen ion
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    precorrin-2 dehydrogenase activity
    methyltransferase activity
    Process
    chlorophyll metabolic process
    cofactor biosynthetic process
    oxidation-reduction process
    porphyrin-containing compound biosynthetic process
    metabolic process
    Gene Properties
    Locus tag: PA1778
    Strand: -
    Entrez Gene ID: 877770
    Accession: NP_250469.1
    GI: 15596975
    Sequence start: 1922295
    Sequence End: 1923032
    Sequence Length: 737
    Gene Sequence: 
    >PA1778
ATGAGCGGTAAGGTCTGGCTGGTGGGTGCGGGTCCCGGCGATCCGGAACTGTTGACCCTGAAGGCAGTTCGCGCCCTGCAGGACGCGGATGTGGTGATGGTCGACGATCTGGTCAACCCGAGCATACTGGAGCACTGTCCGTCCGCCCGGCTGGTCCGGGTCGGCAAACGCGGCGGCTGCCGCTCCACACCGCAGGACTTCATCCAGCGCCTGATGCTGCGGCATGCCCGCCAGGGACGCAGCGTGGTGCGCCTGAAAGGCGGCGATCCATGCATCTTCGGCCGCGCCGGCGAAGAAGCCGAATGGCTGGCCCGGCACGGGATAGACAGCGAGATAGTGAACGGCATCACCGCCGGGCTGGCTGGCGCCACTGCCTGCGGCATACCGCTGACCTACCGCGGCATCAGCCGCGGCGTGACCCTGGTGACCGCGCATACCCAGGACGACAGCCCGCTGGCCTGGGAAGCCCTGGCACGCAGCGGTACCACGCTGGTGGTCTACATGGGCGTCGCCCGTCTCGCAGAGATCCAGGCCGGGCTGCTGGCTGGAGGTATGGCCGAGGATACGCCGCTGGCGATGATCGAGAACGCCACCCTGGGCAACCAGCGCGAATGCCGCAGCAACCTCGGCGAGCTACTGCGGGACGCCGGACGTTTCGCCTTGAAAAGCCCGGCGATCCTGGTGATCGGCGAAGTAACCCGCGACATCGTGTCGCAACCGATTTCCCTGAGCGCCTGA
    Protein Properties
    Protein Residues: 245
    Protein Molecular Weight: 25.9 kDa
    Protein Theoretical pI: 7.41
    Hydropathicity (GRAVY score): 0.091
    Charge at pH 7 (predicted): 0.81
    Protein Sequence: 
    >PA1778
MSGKVWLVGAGPGDPELLTLKAVRALQDADVVMVDDLVNPSILEHCPSARLVRVGKRGGCRSTPQDFIQRLMLRHARQGRSVVRLKGGDPCIFGRAGEEAEWLARHGIDSEIVNGITAGLAGATACGIPLTYRGISRGVTLVTAHTQDDSPLAWEALARSGTTLVVYMGVARLAEIQAGLLAGGMAEDTPLAMIENATLGNQRECRSNLGELLRDAGRFALKSPAILVIGEVTRDIVSQPISLSA
    References
    External Links:
    Resource Link
    Genome ID: PA1778
    Entrez Gene ID: 877770
    NCBI Protein ID: 15596975
    General Reference: PaperBLAST - Find papers about PA1778 and its homologs