Identification
Name: Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive
Synonyms:
  • 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase
  • DAHP synthase
  • Phospho-2-keto-3-deoxyheptonate aldolase
Gene Name: aroF
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
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SMPDB Reactions:
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PseudoCyc/BioCyc Reactions:
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Complex Reactions:
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0008882-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphateMetaboCard
PAMDB0062993-deoxy-D-arabino-heptulosonate-7-phosphateMetaboCard
PAMDB000460D-Erythrose 4-phosphateMetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB000111Phosphoenolpyruvic acidMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
3-deoxy-7-phosphoheptulonate synthase activity
catalytic activity
transferase activity
transferase activity, transferring alkyl or aryl (other than methyl) groups
Process
aromatic amino acid family biosynthetic process
biosynthetic process
cellular amino acid and derivative metabolic process
cellular amino acid biosynthetic process
cellular amino acid metabolic process
cellular metabolic process
metabolic process
Gene Properties
Locus tag: PA1750
Strand: -
Entrez Gene ID: 882053
Accession: NP_250441.1
GI: 15596947
Sequence start: 1890739
Sequence End: 1891815
Sequence Length: 1076
Gene Sequence:
>PA1750
ATGGCTGATTTACAGATCGACGACCTTAACGTTGCCTCCAACGAGACCCTGATCACGCCGGAGCAGCTCAAGCGTGAAATTCCCCTGACCGACAAGGCCCTGCAGACCGTGGCCCAGGGTCGCCAGGTGGTGCGCGACATCCTGGATGGCAAGGACCACCGTCTGTTCGTGGTGATCGGCCCCTGCTCCATCCACGACATCAAGGCCGCCCACGAATACGCCGACCGCCTCAAGGCGCTCGCGGCCGAAGTGGCGGATACGCTGTTCCTGGTGATGCGCGTGTACTTCGAGAAGCCGCGTACCACGGTGGGCTGGAAAGGCCTGATCAACGATCCGTACCTGGACGACTCGTTCAAGATCCAGGATGGCCTGCACATCGGCCGCCAACTGCTCCGCGACCTTGCCGAGAAAGGCTTGCCCACCGCCACCGAAGCGCTCGACCCGATTTCCCCGCAGTACCTGCAGGACCTGATCAGTTGGTCGGCGATCGGCGCCCGTACCACCGAATCGCAGACTCACCGCGAGATGGCCTCCGGCCTGTCTTCCGCGGTCGGCTTCAAGAACGGCACCGATGGCAGCCTGACCGTGGCGATCAATGCCCTGCAGTCGGTCTCCAGCCCGCATCGCTTCCTCGGCATCAACCAGCAGGGCGGCGTGTCCATCGTGACCACCAAGGGCAACCGCTACGGTCACGTGGTGTTGCGCGGCGGCAACGGCAAGCCGAACTACGATTCGGTCAGCGTCGCGCTCTGCGAGCAGGACCTGAACAAGGCGAAAATCCCGCTGAACATCATGGTCGACTGCAGCCACGCCAACTCCAACAAGGACCCGGCCCTGCAACCGCTGGTGATGGACAACGTCAGCAACCAGATCGTCGAAGGCAACAACTCGATCGTCGGCCTGATGGTGGAAAGCCACCTGGGCTGGGGCAGCCAGCCGATTCCGAAGGATCTCGACCAACTTCAGTACGGCGTCTCCATCACCGACGCCTGCATCGACTGGGCGACCACCGAGAAGAGCATCCGCAGCATGCACGCCAAGCTCAAGGACGTGCTGCCGAAACGCCAGCGCGGCTGA
Protein Properties
Protein Residues: 358
Protein Molecular Weight: 39.1 kDa
Protein Theoretical pI: 6.51
Hydropathicity (GRAVY score): -0.256
Charge at pH 7 (predicted): -2.71
Protein Sequence:
>PA1750
MADLQIDDLNVASNETLITPEQLKREIPLTDKALQTVAQGRQVVRDILDGKDHRLFVVIGPCSIHDIKAAHEYADRLKALAAEVADTLFLVMRVYFEKPRTTVGWKGLINDPYLDDSFKIQDGLHIGRQLLRDLAEKGLPTATEALDPISPQYLQDLISWSAIGARTTESQTHREMASGLSSAVGFKNGTDGSLTVAINALQSVSSPHRFLGINQQGGVSIVTTKGNRYGHVVLRGGNGKPNYDSVSVALCEQDLNKAKIPLNIMVDCSHANSNKDPALQPLVMDNVSNQIVEGNNSIVGLMVESHLGWGSQPIPKDLDQLQYGVSITDACIDWATTEKSIRSMHAKLKDVLPKRQRG
References
External Links:
Resource Link
Genome ID: PA1750
Entrez Gene ID: 882053
NCBI Protein ID: 15596947
General Reference: PaperBLAST - Find papers about PA1750 and its homologs