Identification
Name: probable 2-isopropylmalate synthase
Synonyms: Not Available
Gene Name: Not Available
Enzyme Class: Not Available
Biological Properties
General Function: carboxylic acid metabolic process
Specific Function: catalytic activity, transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb
3-methyl-2-oxobutanoate + acetyl-CoA + H2O → (2S)-2-isopropylmalate + coenzyme A + H+
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites: Not Available
GO Classification:
Function
catalytic activity
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
Process
carboxylic acid metabolic process
Gene Properties
Locus tag: PA1217
Strand: -
Entrez Gene ID: 879659
Accession: NP_249908.1
GI: 15596414
Sequence start: 1318147
Sequence End: 1319514
Sequence Length: 1367
Gene Sequence:
>PA1217
ATGATCCGGGTCATCGACTGCACCCTGCGCGAGGGGTGCCAGGCCCGCCAGTGCAGCTTCGACAGCGCGCAGTCGGTCCAGCTGGCGAGGGAAATCGCGGCGCTGGGGGTGGATATGATCGAGTGCGGCCACCCGCGGATTTCCGCGGACGAACGCGAGCGGGTACGCGCCGTGGTGGCGGCGGTTTCCACGCCGGTGCTGGCCCACGCCCGGGCGCGCCGGGAGGATATCGACGCGGTGCTGGAAACCGGTGCGCAGTGGGTCGGGCTGTTCGCCTCGATCAACGCGATCTCGCTGGAAACCAAGTTCAAGGGCATGAACCGCGAGGAGGTGCTCGAACTGTTCCACGACGCGATCCGCTACGCCCGCGAACGCGGCCTGCGGGTCCGGGCCACGGTGGAAGACGCCGCGCGCACCTCGGTCAGCGACCTGGTCAGCATGATCGCCACCGCGCGCGACGCCGGCGCCGATCGCATCTGCTTCGCCGACAGCGTGGGCATCCTGCTGCCGGACGAGACCTTCGACGTGCTCTCGCTGCTGCGCCACGAGTTCCCCGACGTGGTCTTCGAGTACCACGTGCACAACGACCGCGGCCTGGCCCTGGGCAACACCCTGGCGGCGATCCAGGCCGGGGTCCAGTGGCACTCGGCGAGCTGCAACGGGATCGGCGAACGCGCCGGGATCACCGATACCTTCCAGTTGCTGACCCTGCTGCACACCAAGTTCGCCGCCGACCGCTTCAACCTGAAGAACGTCCTCGCGGTCTCCGAGCTGGTCGAGGCGCACAGCCGGATCAAGCGTTCGCCGATGCACCCGGTGGTCGGCGAGAACGCCTTCGTCCATGTCGCCCGCCTGCACCAGTTGGCCATGCAGGAAAACCAGGACGCCTACAGCGCCTTCGATCCGGAACTGATCAACGGCCGCGTCTCGCTGCAACGCTACACGCCGATGCACCGCCAATCCCTGTTCCTCACGCCTTTCGAGAAATCCGCCAGCGAACTGAAGTACCACCGCCACGGCCCCGGCAAGCGCTTCGTCATGCTCGACCGGCGCCTGCTCGACGGCTCGCCGTTCTATTTCATCGCCCGCCAGTTCCACGACGTCGGCGACGGCGGGCCGGGCCACGTCGACAGCCACGTGCACAACTGCGACTCGGTGTTCCTGTTCCTCGGCAGCGACGAGGACTACCGCGGCCTGGAGGTGGAAGTCCTGCTCGGCGGCCAACTGCGCCGTTTGCAAAGCCCGGCCAGCGTGTTCATCCCCGCCGGCGTCGAGCACAGCTACCGCTACCTCGGCGGCAGCGGCACCTACATCAATTTCGTCCACAAGGGCGATTACCACGAGAGCCTACTGGAGATTACCCAATGA
Protein Properties
Protein Residues: 455
Protein Molecular Weight: 50.7 kDa
Protein Theoretical pI: 6.51
Hydropathicity (GRAVY score): -0.145
Charge at pH 7 (predicted): -5.9
Protein Sequence:
>PA1217
MIRVIDCTLREGCQARQCSFDSAQSVQLAREIAALGVDMIECGHPRISADERERVRAVVAAVSTPVLAHARARREDIDAVLETGAQWVGLFASINAISLETKFKGMNREEVLELFHDAIRYARERGLRVRATVEDAARTSVSDLVSMIATARDAGADRICFADSVGILLPDETFDVLSLLRHEFPDVVFEYHVHNDRGLALGNTLAAIQAGVQWHSASCNGIGERAGITDTFQLLTLLHTKFAADRFNLKNVLAVSELVEAHSRIKRSPMHPVVGENAFVHVARLHQLAMQENQDAYSAFDPELINGRVSLQRYTPMHRQSLFLTPFEKSASELKYHRHGPGKRFVMLDRRLLDGSPFYFIARQFHDVGDGGPGHVDSHVHNCDSVFLFLGSDEDYRGLEVEVLLGGQLRRLQSPASVFIPAGVEHSYRYLGGSGTYINFVHKGDYHESLLEITQ
References
External Links:
Resource Link
Genome ID: PA1217
Entrez Gene ID: 879659
NCBI Protein ID: 15596414
General Reference: PaperBLAST - Find papers about PA1217 and its homologs