QuiP acyl-homoserine lactone acylase, QuiP; QuiP (changed from probable penicillin amidase) (PA1032)

Identification
Name: QuiP acyl-homoserine lactone acylase, QuiP; QuiP (changed from probable penicillin amidase)
Synonyms: pac
Gene Name: quiP
Enzyme Class: Not Available
Biological Properties
General Function: antibiotic biosynthetic process
Specific Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides, hydrolase activity
Cellular Location: Periplasmic
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Acyl-homoserine-lactones+PAMDB000142 → PAMDB120339+Carboxylates
    Acyl-homoserine-lactones + Water → L-homoserine lactone + Carboxylates
    ReactionCard
    Thumb
    a penicillin + H2O = 6-aminopenicillanate + a carboxylate
    ReactionCard
    PAMDB120203+PAMDB000142 → PAMDB120339+PAMDB110738
    HAI-1 + Water → L-homoserine lactone + (R)-3-hydroxybutanoate
    ReactionCard
    PAMDB120492+PAMDB000142 → PAMDB120339+PAMDB120316
    AAI + Water → L-homoserine lactone + 3-oxooctanoate
    ReactionCard
    PAMDB120095+PAMDB000142 → PAMDB120339+PAMDB110758
    VAI-2 + Water → L-homoserine lactone + octanoate
    ReactionCard
    PAMDB120378+PAMDB000142 → PAMDB120339+PAMDB120432
    VAI-1 + Water → L-homoserine lactone + 3-oxohexanoate
    ReactionCard
    PAMDB120587+PAMDB000142 → PAMDB120339+PAMDB110757
    PAI-2 + Water → L-homoserine lactone + butanoate
    ReactionCard
    PAMDB100010+PAMDB000142 → PAMDB120339+PAMDB120548
    N-(3-oxododecanoyl)-L-homoserine lactone + Water → L-homoserine lactone + 3-oxo-dodecanoate
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    hydrolase activity
    Process
    antibiotic biosynthetic process
    Gene Properties
    Locus tag: PA1032
    Strand: -
    Entrez Gene ID: 880272
    Accession: NP_249723.1
    GI: 15596229
    Sequence start: 1119674
    Sequence End: 1122217
    Sequence Length: 2543
    Gene Sequence: 
    >PA1032
ATGGCCTCGCCAGCCTTCATGCGTTTTCTTCCCCGTTGCGGCGCCGCCGCGGCCTTCGGCACCCTCCTGGGCCTGGCCGGTTGCCAGTCCTGGCTCGACGATCGCTACGCCGACAGCCTGCCGCCGACCTCCGGCGTACAACCGATCAAGGGCCTGGCGCAAAACGTATCGATCCGGCGCAACGCGCTGGGCATGCCACTGATCGAAACCGGCACCTTCCATGACGCGCTGTTCGCCCTGGGCTACGTACACGCCTCCGACCGCCTGAGCCAGATGGTCAGCCTGCGCCTGCTGGCCCAGGGACGGCTGGCCGAGATGGTCGGCCCCGGCGCGCTGGAGATCGACCGTTTCATGCGTACCGTGAACCTGCGCCAGGCTGCGGAGATCCAGTACAGGAACGCCTCGCCGCGCCTGCAACGCTTCTTCGAGGTCTACGCGCGCGGGGTCAACGCCTACCTGTATCGCTATCGCGACAAGCTGCCGATGGACCTGGCCCAGTCCGGCTACCGTCCGGAATACTGGAAGCCCGAGGACTCGGCGCTGGTCTTCGCCCTGCTCAACTTCGGCCTGGCGGTGAACCTGCAGGAAGAAATCGCCTCGCTGACGCTCGCGCAGAAGGTCGGCAGCGACAAGCTGGCCTGGCTGACGCCGACCTATCCCGACGAAAACCTGCCGTTCGACGAGGCGGAAAAGCTCAAGGGCCTGCGCCTGGACGGGCAGGTTCCCGGCCTCGCGGGCGTCGAGGGCGCGGCGCGGCAGGTCGCAGCGCTGAGCATGCTCGGGGTCGCCGCCTCGAACAACTGGGCTATCGCGCCGCAACGCAGCCGCAGCGGCAAGAGCCTGATGGCCAACGACACCCACCTGCCGCTGAGCATGCCGTCGGTGTGGAACTACGTGCAGATCCGCTCGCCCAAGTACCAGGCCGCGGGCGTTTCCATCGCCGGTCTGCCGGGCGTGGTGGCGGGCTTCAACGGCAAGCTGGCCTGGGGCATGACCATGGTCCTGGGCGACAACCAGGATCTCTACCTGGAACAGCTGCGACGCCAGGGCAACCGGCTCTATTACCTGGCCGACGGCAAGTGGCAGCCAACCCGCGAACGCCAGGAAACCTTCTTCATCAAGGGCCAGCGGCCGATCCGCGAGGTCATCCACGAAACCCGCCATGGCCCGCTGCTCAACAGCGCCCTGGGCGAGCGCAAGAACATCCTCCAGCCGCTGCCGCTGAAGAGCGGCTACGGACTGGCCTACCGGAGCATCCAGCAGGAAGCCGACAAGACCCTGGACGGCTTCTTCGACCTGTCGCGGGCCAAGACCATCGAGCAGGCCTTCGACGCCACCCGCGAGATTCGCGCGATGCCGCTGAACATCGTGTTCGCCGACGAAAAGCACATCGGCTGGCAGGTCACCGGACGCTATCCGAACCGCAAGGAAGGTCGTGGCCTGCTGCCCTCCCCTGGCTGGGACGGCCGCTACGACTGGGATGGCTATGCCGACCCGATCCTCCACCCGTCCGACCAGGACCCGCAGCAGGGCTGGCTGGGTACCGCCAACCACCGCACCGTGCAGCCCGGCTACGGCGCCCAGTTGTCCAATTCCTGGTACTACCCGGAGCGCGCCGAGCGCATCGCCCAGCTCGCCGGTGCCAGCAAGAGCCACGACACCCAGAGCATGATCCGCATGCAGTACGACCAGACCTCGCTGTTCGTCGCCAAGCTGCAAGCCATGTTCGACAATCCCGGCATGGCGCTGCCGCTGCGCCAGGCCATCGACGCCTTGCCGGAGGCGCAACGCAGCCGGGCGCGGGAGGCCTACGACCGGCTGATGGCGTTCGACGGCAAGCTGACAGCCAGCTCCAGCGACGCCGCGCTGTACGGCGCCTTCCTCCACGAGAGCGCCAGGCAGATATTCCTCGACGAGCTAGGACCGGAGGACGGCCCTGCCTGGAAAGCCTTCGTCGAGACCGCCAACCTCTCCTACTCGGCGCAAGCCGACCACCTGCTCGGGCGCGACGACAGTCCGTTCTGGGACGATACCCGCACTCCGCAGAAGGAGGACAAGCCGGCAATCCTCGCGCGCAGCCTCGCCGCCGCCGTGGAGTTCTGCGAACAGCGACTGGGGAGCGAGCGCAAGGCCTGGCAATGGGGCAAGCTGCACACCTACGAATGGCAGAGCGACAGCTCGAAAATGGCCCCCTACCTGGGCGCCGGCGAGCGCGCCGGACTCGGCGCGATCAAGGGCTATCTCGATCGCGGACCCTATCCGGCCGGCGGCGACCACACCACGCTGGACGTATCGGCCTACGGCTGGGGCCAGGACTTCGACACTTGGCTGATCCCGGCGATGCGGCTGATCGTCGACTTCGGCCAGAGCGAACCGATGATCGGCGTGAACAGCAGCGGCCAATCCGGCAATCCGGCCAGCCCGCACTACGCCGACGGTATCGACGCCTGGCTCAAGGGGCGCTACGTTAGCTTCCCGTTCCAGCCACAGAACCTCGATCGCGTTTACGGCAACAAGCGGCTGACGCTCACTCCCGCTCGCTGA
    Protein Properties
    Protein Residues: 847
    Protein Molecular Weight: 94.1 kDa
    Protein Theoretical pI: 7.75
    Hydropathicity (GRAVY score): -0.41
    Charge at pH 7 (predicted): 3.31
    Protein Sequence: 
    >PA1032
MASPAFMRFLPRCGAAAAFGTLLGLAGCQSWLDDRYADSLPPTSGVQPIKGLAQNVSIRRNALGMPLIETGTFHDALFALGYVHASDRLSQMVSLRLLAQGRLAEMVGPGALEIDRFMRTVNLRQAAEIQYRNASPRLQRFFEVYARGVNAYLYRYRDKLPMDLAQSGYRPEYWKPEDSALVFALLNFGLAVNLQEEIASLTLAQKVGSDKLAWLTPTYPDENLPFDEAEKLKGLRLDGQVPGLAGVEGAARQVAALSMLGVAASNNWAIAPQRSRSGKSLMANDTHLPLSMPSVWNYVQIRSPKYQAAGVSIAGLPGVVAGFNGKLAWGMTMVLGDNQDLYLEQLRRQGNRLYYLADGKWQPTRERQETFFIKGQRPIREVIHETRHGPLLNSALGERKNILQPLPLKSGYGLAYRSIQQEADKTLDGFFDLSRAKTIEQAFDATREIRAMPLNIVFADEKHIGWQVTGRYPNRKEGRGLLPSPGWDGRYDWDGYADPILHPSDQDPQQGWLGTANHRTVQPGYGAQLSNSWYYPERAERIAQLAGASKSHDTQSMIRMQYDQTSLFVAKLQAMFDNPGMALPLRQAIDALPEAQRSRAREAYDRLMAFDGKLTASSSDAALYGAFLHESARQIFLDELGPEDGPAWKAFVETANLSYSAQADHLLGRDDSPFWDDTRTPQKEDKPAILARSLAAAVEFCEQRLGSERKAWQWGKLHTYEWQSDSSKMAPYLGAGERAGLGAIKGYLDRGPYPAGGDHTTLDVSAYGWGQDFDTWLIPAMRLIVDFGQSEPMIGVNSSGQSGNPASPHYADGIDAWLKGRYVSFPFQPQNLDRVYGNKRLTLTPAR
    References
    External Links:
    Resource Link
    Genome ID: PA1032
    Entrez Gene ID: 880272
    NCBI Protein ID: 15596229
    General Reference: PaperBLAST - Find papers about PA1032 and its homologs