Transketolase 1 (PA0548)

Identification
Name: Transketolase 1
Synonyms:
  • TK 1
Gene Name: tktA
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb
D-Erythrose 4-phosphate + Xylulose 5-phosphate ↔ Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate ↔ D-Erythrose 4-phosphate + Xylulose 5-phosphate
ReactionCard
Sedoheptulose 7-phosphate+Thumb+Thumb ↔ Thumb+Thumb
Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate + D-Sedoheptulose 7-phosphate ↔ D-Ribose-5-phosphate + Xylulose 5-phosphate
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
beta-D-Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate ↔ D-Erythrose 4-phosphate + Xylulose 5-phosphate
ReactionCard
Aminofructose 6-phosphate+Thumb ↔ Iminoerythrose 4-phosphate+Sedoheptulose 7-phosphate
Aminofructose 6-phosphate + D-Ribose-5-phosphate ↔ Iminoerythrose 4-phosphate + Sedoheptulose 7-phosphate
ReactionCard
SMPDB Reactions:
Xylulose 5-phosphate+Thumb+Thumb ↔ D-Sedoheptulose 7-phosphate+D-Glyceraldehyde 3-phosphate+Thumb+Thumb
Xylulose 5-phosphate + D-Ribose-5-phosphate + Xylulose 5-phosphate ↔ D-Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate + D-Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb
D-Ribose-5-phosphate + Xylulose 5-phosphate ↔ D-Glyceraldehyde 3-phosphate + D-Sedoheptulose 7-phosphate
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
D-Erythrose 4-phosphate + Xylulose 5-phosphate ↔ Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000547beta-D-Fructose 6-phosphateMetaboCard
PAMDB000460D-Erythrose 4-phosphateMetaboCard
PAMDB000257D-Glyceraldehyde 3-phosphateMetaboCard
PAMDB000431D-Ribose-5-phosphateMetaboCard
PAMDB000240D-Sedoheptulose 7-phosphateMetaboCard
PAMDB000047Fructose 6-phosphateMetaboCard
PAMDB000653Xylulose 5-phosphateMetaboCard
GO Classification:
Function
catalytic activity
transferase activity
transferase activity, transferring aldehyde or ketonic groups
transketolase activity
Process
metabolic process
Gene Properties
Locus tag: PA0548
Strand: +
Entrez Gene ID: 878523
Accession: NP_249239.1
GI: 15595745
Sequence start: 606160
Sequence End: 608157
Sequence Length: 1997
Gene Sequence: 
>PA0548
ATGCCCAGCCGTCGTGAGCGAGCCAATGCCATCCGTGCACTGAGCATGGATGCCGTGCAGAAAGCCAACAGCGGCCACCCGGGCGCCCCGATGGGCATGGCCGATATCGCCGAGGTCCTCTGGCGCGACTACATGCAGCACAACCCGAGCAACCCGCAGTGGGCCAACCGCGACCGCTTCGTGCTGTCCAACGGCCACGGCTCGATGCTGATCTACTCCCTGCTGCACCTCACCGGGTACGACCTCGGCATCGAGGACCTGAAGAACTTCCGCCAGCTCAACTCGCGCACCCCGGGCCACCCGGAGTACGGCTACACCGCCGGCGTCGAGACCACCACCGGTCCGCTCGGCCAGGGCATCGCCAATGCGGTGGGCATGGCGCTGGCGGAGAAGGTCCTGGCCGCCCAGTTCAACCGCGACGGCCACGCGGTGGTCGACCACTACACCTACGCCTTCCTCGGCGACGGCTGCATGATGGAAGGCATTTCCCATGAGGTCGCCTCGCTGGCCGGCACCCTGCGCCTGAACAAGCTGATCGCCTTCTACGACGACAACGGCATTTCCATCGACGGCGAGGTCCACGGCTGGTTCACCGACGACACCCCGAAGCGCTTCGAGGCCTATGGCTGGCAAGTGATCCGCAACGTCGACGGGCATGACGCCGACGAGATCAAGACCGCCATCGATACCGCGCGCAAGAGCGACCAGCCGACCCTGATCTGCTGCAAGACCGTGATCGGTTTCGGCTCGCCGAACAAGCAGGGCAAGGAAGAGTGCCACGGCGCGCCGCTGGGCGCCGACGAGATCGCCGCGACCCGCGCCGCGCTGGGCTGGGAGCACGCTCCGTTCGAGATCCCGGCGCAGATCTACGCCGAGTGGGACGCCAAGGAAACCGGCGCCGCCCAGGAAGCCGAGTGGAACAAGCGTTTCGCCGCCTACCAGGCTGCCCATCCGGAACTGGCCGCCGAATTGCTGCGCCGCCTGAAGGGCGAGCTGCCGGCCGACTTCGCCGAGAAGGCCGCGGCCTACGTCGCCGATGTTGCCAACAAGGGTGAGACCATCGCCAGCCGCAAGGCCAGCCAGAACGCGCTGAACGCCTTCGGCCCGCTGCTGCCGGAGCTGCTCGGCGGTTCCGCCGACCTGGCCGGCTCCAACCTGACCTTGTGGAAGGGCTGCAAGGGCGTCAGCGCCGACGACGCCGCCGGCAACTACGTGTTCTACGGCGTGCGCGAATTCGGCATGAGCGCGATCATGAATGGCGTCGCCCTGCACGGCGGTTTCATTCCCTACGGTGCGACCTTCCTGATCTTCATGGAATACGCGCGCAACGCCGTGCGCATGTCCGCACTGATGAAGCAGCGCGTGCTCTACGTGTTCACCCACGACTCCATCGGCCTCGGCGAGGACGGCCCGACCCACCAGCCGATCGAACAACTGGCCAGCCTGCGCCTGACCCCGAACCTGGACACCTGGCGCCCGGCCGACGCGGTCGAGTCGGCGGTGGCCTGGAAGCATGCCATCGAGCGCGCCGACGGTCCGTCCGCGCTGATCTTCTCCCGCCAGAACCTGCCGCACCAGGCGCGCGACGTCGCCCAGGTGGCCGACATCGCCCGCGGCGGCTACGTGCTGAAGGACTGCGAAGGCGAGCCGGAACTGATCCTGATCGCCACCGGTTCGGAAGTCGGCCTGGCCGTGCAGGCCTACGACAAGCTCAGCGAGCAGGGCCGCAAGGTCCGCGTGGTATCGATGCCATGCACCAGCGTCTACGAGCAGCAGGACGAGTCCTACAAGCAGTCCGTGCTGCCGGTGGAAGTCGGCGCGCGCATCGCCATCGAGGCCGCCCATGCCGACTACTGGTACAAGTACGTCGGTCTCGACGGGCGCATCATCGGCATGACCAGCTTCGGCGAGTCGGCGCCGGCCCCGGCGCTGTTCGAGCACTTCGGCTTCACCCTGGACAACGTCCTGGCGGTGGCCGAGGAGCTGCTGGAAGACTGA
Protein Properties
Protein Residues: 665
Protein Molecular Weight: 72.2 kDa
Protein Theoretical pI: 4.97
Hydropathicity (GRAVY score): -0.212
Charge at pH 7 (predicted): -23.37
Protein Sequence: 
>PA0548
MPSRRERANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRDYMQHNPSNPQWANRDRFVLSNGHGSMLIYSLLHLTGYDLGIEDLKNFRQLNSRTPGHPEYGYTAGVETTTGPLGQGIANAVGMALAEKVLAAQFNRDGHAVVDHYTYAFLGDGCMMEGISHEVASLAGTLRLNKLIAFYDDNGISIDGEVHGWFTDDTPKRFEAYGWQVIRNVDGHDADEIKTAIDTARKSDQPTLICCKTVIGFGSPNKQGKEECHGAPLGADEIAATRAALGWEHAPFEIPAQIYAEWDAKETGAAQEAEWNKRFAAYQAAHPELAAELLRRLKGELPADFAEKAAAYVADVANKGETIASRKASQNALNAFGPLLPELLGGSADLAGSNLTLWKGCKGVSADDAAGNYVFYGVREFGMSAIMNGVALHGGFIPYGATFLIFMEYARNAVRMSALMKQRVLYVFTHDSIGLGEDGPTHQPIEQLASLRLTPNLDTWRPADAVESAVAWKHAIERADGPSALIFSRQNLPHQARDVAQVADIARGGYVLKDCEGEPELILIATGSEVGLAVQAYDKLSEQGRKVRVVSMPCTSVYEQQDESYKQSVLPVEVGARIAIEAAHADYWYKYVGLDGRIIGMTSFGESAPAPALFEHFGFTLDNVLAVAEELLED
References
External Links:
Resource Link
Genome ID: PA0548
Entrez Gene ID: 878523
NCBI Protein ID: 15595745
General Reference: PaperBLAST - Find papers about PA0548 and its homologs