Identification
Name: Disulfide bond formation protein B
Synonyms:
  • Disulfide oxidoreductase
Gene Name: dsbB
Enzyme Class: Not Available
Biological Properties
General Function: Involved in protein disulfide oxidoreductase activity
Specific Function: Required for disulfide bond formation in some periplasmic proteins such as phoA or ompA. Acts by oxidizing the dsbA protein
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Protein-Red-DisulfidesProtein-Ox-Disulfides
    Protein-Red-Disulfides ↔ Protein-Ox-Disulfides
    ReactionCard
    Complex Reactions:
    Thumb+periplasmic protein disulfide isomerase I (reduced)Thumb+periplasmic protein disulfide isomerase I (oxidized)
    Ubiquinone-8 + periplasmic protein disulfide isomerase I (reduced) → Ubiquinol-8 + periplasmic protein disulfide isomerase I (oxidized)
    ReactionCard
    Menaquinone 8+periplasmic protein disulfide isomerase I (reduced)Thumb+periplasmic protein disulfide isomerase I (oxidized)
    Menaquinone 8 + periplasmic protein disulfide isomerase I (reduced) → Menaquinol 8 + periplasmic protein disulfide isomerase I (oxidized)
    ReactionCard
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB001653Menaquinol 8MetaboCard
    PAMDB000237Ubiquinol-8MetaboCard
    PAMDB001700Ubiquinone-8MetaboCard
    GO Classification:
    Component
    cell part
    membrane
    Function
    catalytic activity
    disulfide oxidoreductase activity
    oxidoreductase activity
    oxidoreductase activity, acting on a sulfur group of donors
    protein disulfide oxidoreductase activity
    Gene Properties
    Locus tag: PA0538
    Strand: -
    Entrez Gene ID: 878500
    Accession: NP_249229.1
    GI: 15595735
    Sequence start: 596970
    Sequence End: 597479
    Sequence Length: 509
    Gene Sequence:
    >PA0538
    TTGAGCGCTCTCCTCAAGCCCCTCGACAATCGCTTGTTCTGGCCCGCGGTCGCCATCGGCGGCCTGCTGATCCTCGCTTTCGTCCTCTACCTCCAGCACGTGCGCGGCTTCGCGCCCTGCTCGCTGTGCATCTTCATTCGCCTGGACGTGCTCGGCCTGGTGCTCGCCGGGATCGTCGGCAGCCTCGCCCCGCGTTCGCGGATCGCCGGCGGCATCGCCGCGCTGGGCATGCTCGCCGCCAGCCTGGGCGGGATCTACCACGCCTGGTCGCTGGTCGCGGAAGAGAAACTGGCTGCCCAGGGCATGGGCAGTTGCAAGATGTTCATGGGCTTCCCCGAATGGATACCGCTGGATACCTGGCTGCCGCAGGTCTTCCAGCCCGAGGGGCTGTGCGGCGAAGTGGTCTGGACCCTGCTCGGCCAGTCCATGGCGGTCTGGTCGCTGGCGCTGTTCGTGTTCTGCCTGCTGGTCCTGGCGGCCAAGCTGGCGTTCGGCCGCCGCACCGCCTGA
    Protein Properties
    Protein Residues: 169
    Protein Molecular Weight: 18.1 kDa
    Protein Theoretical pI: 8.5
    Hydropathicity (GRAVY score): 0.985
    Charge at pH 7 (predicted): 3.31
    Protein Sequence:
    >PA0538
    MSALLKPLDNRLFWPAVAIGGLLILAFVLYLQHVRGFAPCSLCIFIRLDVLGLVLAGIVGSLAPRSRIAGGIAALGMLAASLGGIYHAWSLVAEEKLAAQGMGSCKMFMGFPEWIPLDTWLPQVFQPEGLCGEVVWTLLGQSMAVWSLALFVFCLLVLAAKLAFGRRTA
    References
    External Links:
    Resource Link
    Genome ID: PA0538
    Entrez Gene ID: 878500
    NCBI Protein ID: 15595735
    General Reference: PaperBLAST - Find papers about PA0538 and its homologs