ATP-independent RNA helicase dbpA (PA0455)

Identification
Name: ATP-independent RNA helicase dbpA
Synonyms: Not Available
Gene Name: dbpA
Enzyme Class:
Biological Properties
General Function: Replication, recombination and repair
Specific Function: Has a helix-destabilizing activity, which is not coupled to the ATPase activity. Can unwind the 23S rRNA as well as 16S rRNA. Exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA. Could play a major role in ribosome assembly, specifically in the assembly process of the active center of 50S ribosomal subunits
Cellular Location: Cytoplasm (Probable)
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Complex Reactions:
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Adenosine triphosphate + Water → ADP + Inorganic phosphate
    ReactionCard
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB000148Adenosine triphosphateMetaboCard
    PAMDB000345ADPMetaboCard
    PAMDB001776Inorganic phosphateMetaboCard
    PAMDB000142WaterMetaboCard
    GO Classification:
    Function
    adenyl nucleotide binding
    adenyl ribonucleotide binding
    ATP binding
    ATP-dependent helicase activity
    ATPase activity
    ATPase activity, coupled
    binding
    catalytic activity
    helicase activity
    hydrolase activity
    hydrolase activity, acting on acid anhydrides
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    nucleic acid binding
    nucleoside binding
    nucleoside-triphosphatase activity
    purine nucleoside binding
    pyrophosphatase activity
    Gene Properties
    Locus tag: PA0455
    Strand: -
    Entrez Gene ID: 881459
    Accession: NP_249146.1
    GI: 15595652
    Sequence start: 513051
    Sequence End: 514427
    Sequence Length: 1376
    Gene Sequence: 
    >PA0455
GTGACCTCCACCGCTTTCTCCTCGCTGCCGCTTTCCGCGGACCTCCTGGCCAATCTCGACTCCCTCGGTTACCGGGAGATGACGCCGATCCAGGCGCAGAGCCTGCCGCTGATCCTCCAGGGCCACGACCTGATCGCCCAGGCCAAGACCGGCAGCGGCAAGACCGCGGCCTTCGGCCTCGCCCTGCTCAGCCCGCTGAACCCGCGCTACTTCGGCTGCCAGGCGCTGGTGCTGTGCCCGACCCGCGAACTGGCCGACCAGGTCGCCAAGGAGATCCGCCGGCTGGCCCGCGCCGCCGACAACATCAAGGTCCTGACCCTCTGCGGCGGCGTCCCCTACGGCCCGCAGGTGGCTTCGCTGGAGCACGGCGCGCACGTGGTGGTCGGCACCCCGGGGCGCATCCAGGAGCACCTGCGCAAGGGCACCCTGGTCCTCGACGGGCTCAATACCCTGGTCCTCGACGAAGCCGACCGGATGCTCGACATGGGCTTCTACGACAGCATCGCCGAGATCATCGGCCAGCTCCCCGAGCGCCGGCAGACCCTGCTGTTCTCCGCCACCTACCCGGACGGCATCGAGAAGCTGGCGAAGACCTTCATGCGCGATCCGCGACAGGTGAGGGTCGAGTCGCTGCACGCCGACAGCCAGATCGAGCAGCGCTTCTTCGAGATCGATCCGAAACAGCGCATGGACGCCGTGGTACGCCTGCTCCAGCATTTCCGGCCACAGTCCTGCGTGGCCTTCTGCCAGACCCGCCAGCAGTGCCAGGAGCTGGCCGACGCACTGAAGGCGCAGCGGATTTCCGCCCTGGCCCTGCACGGCGACCTGGAGCAGCGCGAGCGCGACCAGGTCCTGACGGTGTTCGCCAACCGCAGTTGCAACGTACTGGTGGCCACCGACGTGGCCGCCCGCGGGCTGGACATCGCCGCCCTGGAAACGGTGATCAACGTCGAGCTGGCGCGTGACCCGGAGGTCCACATCCATCGCATCGGACGCAGCGGTCGCGCCGGCGAGAAAGGCCTGGCCCTGTCGCTGGTGGCGCCGGCCGAGGCCAGCCGCGCGCAGGCCATCGAGGACCTGCAGAAGCAGCCGCTGGCCTGGTACGCCCTCGGCCAGTTGAAGGCCAGCCCGGAGCCATTGCTGCCGCCGATGAGCACCCTGTGCATCGCCGGCGGACGCAAGGACAAGGTGCGCCCCGGCGACCTGCTCGGTGCCCTCACCGGCGACGCCGGGCTGCCCGGCAGCGCGGTGGGCAAGATCGCCATCTTCGACTTCCAGGCCTTCGTCGCCATCGAGCGCGGCCTCGCCCACCAGGCCCTCAAGCGCCTGAGCGAAGGCAAGATCAAGGGGCGCTCGTTCAAGGTCCGCCTGCTGTAG
    Protein Properties
    Protein Residues: 458
    Protein Molecular Weight: 49.8 kDa
    Protein Theoretical pI: 8.4
    Hydropathicity (GRAVY score): -0.034
    Charge at pH 7 (predicted): 6.18
    Protein Sequence: 
    >PA0455
MTSTAFSSLPLSADLLANLDSLGYREMTPIQAQSLPLILQGHDLIAQAKTGSGKTAAFGLALLSPLNPRYFGCQALVLCPTRELADQVAKEIRRLARAADNIKVLTLCGGVPYGPQVASLEHGAHVVVGTPGRIQEHLRKGTLVLDGLNTLVLDEADRMLDMGFYDSIAEIIGQLPERRQTLLFSATYPDGIEKLAKTFMRDPRQVRVESLHADSQIEQRFFEIDPKQRMDAVVRLLQHFRPQSCVAFCQTRQQCQELADALKAQRISALALHGDLEQRERDQVLTVFANRSCNVLVATDVAARGLDIAALETVINVELARDPEVHIHRIGRSGRAGEKGLALSLVAPAEASRAQAIEDLQKQPLAWYALGQLKASPEPLLPPMSTLCIAGGRKDKVRPGDLLGALTGDAGLPGSAVGKIAIFDFQAFVAIERGLAHQALKRLSEGKIKGRSFKVRLL
    References
    External Links:
    Resource Link
    Genome ID: PA0455
    Entrez Gene ID: 881459
    NCBI Protein ID: 15595652
    General Reference: PaperBLAST - Find papers about PA0455 and its homologs