P. aeruginosa Metabolome Database Protein PA0447

Identification

Name:

glutaryl-CoA dehydrogenase

Synonyms:

Not Available

Gene Name:

gcdH

Enzyme Class:

Not Available

Biological Properties

General Function:

metabolic process, oxidation-reduction process

Specific Function:

oxidoreductase activity, acting on the CH-CH group of donors, flavin adenine dinucleotide binding, acyl-CoA dehydrogenase activity

Cellular Location:

Cytoplasmic

KEGG Pathways:

L-tryptophan degradation III (eukaryotic) TRYPTOPHAN-DEGRADATION-1
glutaryl-CoA degradation PWY-5177
crotonate fermentation (to acetate and cyclohexane carboxylate) PWY-7401

KEGG Reactions:

Not Available

SMPDB Reactions:

Not Available

PseudoCyc/BioCyc Reactions:

glutaryl-CoA + an oxidized electron-transfer flavoprotein + 2 H⁺ = crotonyl-CoA + CO₂ + a reduced electron-transfer flavoprotein
ReactionCard

glutaryl-CoA + an oxidized electron-transfer flavoprotein + H⁺ ↔ (E)-glutaconyl-CoA + a reduced electron-transfer flavoprotein
ReactionCard

(E)-glutaconyl-CoA + H⁺ ↔ CO₂ + crotonyl-CoA
ReactionCard

Complex Reactions:

Not Available

Transports:

Not Available

Metabolites:

Not Available

GO Classification:

Function
oxidoreductase activity, acting on the CH-CH group of donors
flavin adenine dinucleotide binding
acyl-CoA dehydrogenase activity
Process
metabolic process
oxidation-reduction process

Gene Properties

Locus tag:

PA0447

Strand:

Entrez Gene ID:

880534

Accession:

NP_249138.1

GI:

15595644

Sequence start:

502719

Sequence End:

503900

Sequence Length:

1181

Gene Sequence:

>PA0447
ATGGCCACCAAAGCTAGCTTCAACTGGGAAGATCCCCTGCTGCTGGACCAGCAGCTCACCGAAGAAGAGCGCATGGTTCGCGACAGCGCCCAGCAGTTCGCCCAGGACAAGCTGGCCCCGCGCGTGCTCGAAGCCTTCCGCCACGAACAGACCGACCCGAAGATCTTCCGCGAGATGGGCGAGACCGGCCTGCTCGGCGCGACCATTCCCGAAGCCTACGGCGGCAGCGGCCTCAACTACGTCTGCTATGGCCTGATCGCTCGCGAAGTCGAGCGCGTCGACTCCGGCTATCGCTCGATGATGAGCGTGCAGTCCTCGCTGGTGATGGTGCCGATCCATGAATTCGGCAACGAAGCCACCCGGCAGAAGTACCTGCCCAAGCTGGCCAGCGGCGAATACATCGGCTGCTTCGGCCTGACCGAGCCGAACCACGGTTCCGACCCGGGCTCGATGGTCACCCGGGCGAAGAAGGTCGACGGCGGCTATCGCCTGAGCGGCAGCAAGATGTGGATCACCAACAGCCCGATCGCCGACGTCTTCGTGGTCTGGGCCAAGGATGACGAAGGGCAGATCCGCGGCTTCGTCCTCGAGAAGGGCTGGGAAGGCCTGAGCGCCCCGGCGATCCATGGCAAGGTCGGCCTGCGTGCCTCGATCACCGGCGAGATCGTGATGGACAACGTGTTCGTTCCGGAAGAGAACGCCTTCCCCGAAGTGCGCGGCCTGCGCGGTCCGTTCACCTGCCTGAACTCGGCGCGCTACGGGATCTCCTGGGGCGCCCTGGGCGCCGCCGAATTCTGCTGGCACACCGCCCGCCAGTACGTGCTCGACCGCCAGCAGTTCGGCCGCCCGCTGGCCGCCAACCAACTGATCCAGAAGAAGCTGGCCGACATGCAGACCGAGATCACCCTGGCCCTGCAAGGCTGCCTGCGCCTGGGGCGGATGAAGGACGAAGGCACCGCGGCGGTGGAAATCACCTCGATCATGAAGCGCAACAGCTGCGGCAAGGCCCTCGACATCGCCCGCCTGGCCCGCGACATGCTGGGCGGCAACGGCATCTCCGACGAATTCGGCATCGCCCGCCACCTGGTCAACCTGGAAGTGGTGAACACCTACGAGGGCACCCACGATGTCCACGCGCTGATCCTCGGCCGCGCGCAGACCGGCATCCAGGCATTCTTCTGA

Protein Properties

Protein Residues:

393

Protein Molecular Weight:

43.3 kDa

Protein Theoretical pI:

6.12

Hydropathicity (GRAVY score):

-0.212

Charge at pH 7 (predicted):

-4.25

Protein Sequence:

>PA0447
MATKASFNWEDPLLLDQQLTEEERMVRDSAQQFAQDKLAPRVLEAFRHEQTDPKIFREMGETGLLGATIPEAYGGSGLNYVCYGLIAREVERVDSGYRSMMSVQSSLVMVPIHEFGNEATRQKYLPKLASGEYIGCFGLTEPNHGSDPGSMVTRAKKVDGGYRLSGSKMWITNSPIADVFVVWAKDDEGQIRGFVLEKGWEGLSAPAIHGKVGLRASITGEIVMDNVFVPEENAFPEVRGLRGPFTCLNSARYGISWGALGAAEFCWHTARQYVLDRQQFGRPLAANQLIQKKLADMQTEITLALQGCLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGIARHLVNLEVVNTYEGTHDVHALILGRAQTGIQAFF

References

External Links:

Resource	Link
Genome ID:	PA0447
Entrez Gene ID:	880534
NCBI Protein ID:	15595644

General Reference:

PaperBLAST - Find papers about PA0447 and its homologs

glutaryl-CoA dehydrogenase (PA0447)