Cytosine deaminase (PA0437)

Identification
Name: Cytosine deaminase
Synonyms:
  • Cytosine aminohydrolase
Gene Name: codA
Enzyme Class:
Biological Properties
General Function: Involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Specific Function: Cytosine + H(2)O = uracil + NH(3)
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb
Cytosine + Water ↔ Uracil + Ammonia
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Thumb+Thumb ↔ Thumb+Thumb
5-Methylcytosine + Water ↔ Thymine + Ammonia
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Creatinine+Thumb ↔ N-Methylhydantoin+Thumb
Creatinine + Water ↔ N-Methylhydantoin + Ammonia
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SMPDB Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb
Cytosine + Hydrogen ion + Water → Ammonium + Uracil
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PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb
Cytosine + Water ↔ Uracil + Ammonia
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Complex Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb
Cytosine + Hydrogen ion + Water → Ammonium + Uracil
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Thumb+Thumb → Thumb+Thumb
Cytosine + Water → Uracil + Ammonia
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0004695-MethylcytosineMetaboCard
PAMDB000017AmmoniaMetaboCard
PAMDB001595AmmoniumMetaboCard
PAMDB000161CytosineMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000110ThymineMetaboCard
PAMDB000126UracilMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
catalytic activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Gene Properties
Locus tag: PA0437
Strand: -
Entrez Gene ID: 877586
Accession: NP_249128.1
GI: 15595634
Sequence start: 489387
Sequence End: 490658
Sequence Length: 1271
Gene Sequence: 
>PA0437
ATGCTGATTGACAACCTGCGCCTGCGCGGCCGCGAAGGTCTCTGGCAACTGCGCGTCGCCGATGGCCGTATCGCCGCCCTGGTGCCGATGGAACAGGCCGCCGACGACGCCGGCGAGCGCCTGGACGGCGCCGGCGGTCTTGCCGTGCCGCCGTTCATCGAGCCGCACATCCATCTCGACACCACCCAGACCGCCGGCCAGCCGGAGTGGAACCGCTCCGGCACGCTGTTCGAAGGCATCGAGCGCTGGGCCCAGCGCAAGGCCCTGCTCAGCCACGAGGACGTCAAGCAGCGCGCCTGGCAGACCCTGAAATGGCAGATCGCCAACGGCGTGCAGCACGTGCGCAGCCACGTCGACGTCTCCGACCCGACCCTCACCGCGCTCAAGGCCATGCTCGAGGTGCGCGGCGAAGTGGCGCCCTGGGTCGACCTGCAGATCGTCGCCTTCCCTCAGGAGGGCATTCTCTCCTACCCCAACGGCCTGGAACTGCTGGAGGAGTCGCTGCGCCTGGGCGCCGACGTGGTGGGGGCGATCCCGCATTTCGAATTCACCCGCGAGCTGGGCGTCGAGTCGCTGCACAAGGCCATCGACCTGGCCAAGCGCTACGACCTGCCGGTGGACGTGCATTGCGACGAGATCGACGACGAGCAGTCGCGCTTCCTCGAGACCCTGGCCATGCTCGCCCATCGCGACGGCCTCGGCGCACGGGTCACCGCCAGCCACACCACGGCGATGCACTCCTACAACGGCGCCTACACCTCGCGGCTGTTCCGCCTGCTGAAACTGTCGGGAATCAACTTCGTCGCCAACCCGCTGGTGAACATCCACCTGCAGGGTCGCTTCGACGACTACCCGAAGCGCCGCGGCATCACCCGGGTCAAGGAACTGCTCGGCGCCGGGATCAACACCTGCTTCGGCCACGACGACGTGTTCGACCCCTGGTACCCGCTGGGCACCGCGAACATGCTGCAGGTGCTGCACATGGGCCTGCACGTGACGCAGATGATGGGCTACGACGAGATCGACGGCGGCCTCGACCTGATCACCCGCAACAGCGCCCGCACCCTCGGCCTGCGGGAATACGGCATCGAGGTCGGCCATCCGGCCAACCTGCTGGTGCTGCCGGCCCGCGACGGCTTCGACGCGGTGCGCCGGCAGGTCCCGGTGCGCTACTCGATCCGCGGCGGACGGCTGCTCGCCGAGACGGTCCCGGCGCAGACCACGGTGTTCCTCGAACAGGCGGAAGCGGTGGACTTCACCCGCGCCAGCTGA
Protein Properties
Protein Residues: 423
Protein Molecular Weight: 47.1 kDa
Protein Theoretical pI: 5.96
Hydropathicity (GRAVY score): -0.186
Charge at pH 7 (predicted): -9.19
Protein Sequence: 
>PA0437
MLIDNLRLRGREGLWQLRVADGRIAALVPMEQAADDAGERLDGAGGLAVPPFIEPHIHLDTTQTAGQPEWNRSGTLFEGIERWAQRKALLSHEDVKQRAWQTLKWQIANGVQHVRSHVDVSDPTLTALKAMLEVRGEVAPWVDLQIVAFPQEGILSYPNGLELLEESLRLGADVVGAIPHFEFTRELGVESLHKAIDLAKRYDLPVDVHCDEIDDEQSRFLETLAMLAHRDGLGARVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDDYPKRRGITRVKELLGAGINTCFGHDDVFDPWYPLGTANMLQVLHMGLHVTQMMGYDEIDGGLDLITRNSARTLGLREYGIEVGHPANLLVLPARDGFDAVRRQVPVRYSIRGGRLLAETVPAQTTVFLEQAEAVDFTRAS
References
External Links:
Resource Link
Genome ID: PA0437
Entrez Gene ID: 877586
NCBI Protein ID: 15595634
General Reference: PaperBLAST - Find papers about PA0437 and its homologs