Identification
Name: D-3-phosphoglycerate dehydrogenase
Synonyms:
  • PGDH
Gene Name: serA
Enzyme Class:
Biological Properties
General Function: Involved in amino acid binding
Specific Function: 3-phospho-D-glycerate + NAD(+) = 3- phosphonooxypyruvate + NADH
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+ThumbThumb+Thumb+Thumb
Thumb+ThumbThumb+Thumb
Thumb+Thumb+ThumbThumb+Thumb+Thumb+Thumb
SMPDB Reactions:
3-Phosphoglyceric acid+Thumb+ThumbThumb+Thumb+Thumb
3-Phosphoglyceric acid+Thumb+ThumbThumb+Thumb+Thumb
PseudoCyc/BioCyc Reactions:
Thumb+ThumbThumb+Thumb+Thumb
Complex Reactions:
Thumb+ThumbThumb+Thumb
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0020393-Phospho-D-glycerateMetaboCard
PAMDB0006283-PhosphoglycerateMetaboCard
PAMDB000155D-2-Hydroxyglutaric acidMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000197NADMetaboCard
PAMDB000398NADHMetaboCard
PAMDB000623Oxoglutaric acidMetaboCard
PAMDB000229Phosphohydroxypyruvic acidMetaboCard
GO Classification:
Function
amino acid binding
binding
carboxylic acid binding
catalytic activity
cofactor binding
NAD or NADH binding
nucleotide binding
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Process
metabolic process
Gene Properties
Locus tag: PA0316
Strand: -
Entrez Gene ID: 878305
Accession: NP_249007.1
GI: 15595513
Sequence start: 355248
Sequence End: 356477
Sequence Length: 1229
Gene Sequence:
>PA0316
ATGAGCAAGACCTCTCTCGACAAGAGCAAGATCAAGTTCCTTCTTCTCGAAGGTGTCCACCAGAACGCCGTGGACACGCTGAAGGCCGCCGGCTACACCAACATCGAGTACCTCAAGACCGCGCTTTCCGGCGACGAGCTGAAGGAAAGGATCGCCGATGCGCACTTCATCGGCATTCGCTCCCGCACCCAGCTGACCGAAGAGGTCTTCGACTGCGCGAAGAAACTGATCGCGGTCGGCTGCTTCTGCATCGGCACCAACCAGGTCGACCTCAACGCCGCCCGCGAACGCGGTATCGCCGTGTTCAACGCGCCCTACTCGAACACCCGCTCTGTGGCTGAGCTGGTACTGGCCGAGGCGATCCTGCTGCTGCGCGGCATCCCGGAAAAGAACGCCTCCTGCCATCGCGGCGGCTGGATCAAGAGCGCGGCGAATTCCTTCGAGATCCGTGGCAAGAAGCTCGGCATCGTCGGCTACGGCTCGATCGGCACCCAGCTCTCGGTACTCGCCGAGGCCCTGGGCATGCAGGTGTTCTTCTACGACACCGTGACCAAGCTGCCGCTGGGCAACGCGGTGCAGATCGGCAGCCTGCACGAGCTGCTGGGCATGTCCGACATCGTCTCGCTGCACGTTCCCGAACTGCCCTCCACCCAGTGGATGATCGGCGAGAAGGAAATCCGCGCGATGAAGAAGGGCGGCATCCTGATCAACGCCGCGCGCGGCACAGTGGTCGAGCTGGACCACCTGGCCGCCGCGATCAAGGACGAGCACCTGATCGGCGCCGCCATCGACGTGTTCCCGGTCGAGCCGAAATCCAACGACGAGGAATTCGCCAGCCCGCTGCGTGGCCTGGACCGGGTGATCCTGACCCCGCACATCGGCGGCTCCACCGCCGAGGCACAGGCCAACATCGGCCTGGAAGTGGCGGAGAAGCTGGTCAAGTACAGCGACAACGGCACCTCGGTGTCCTCGGTCAACTTCCCCGAAGTGGCCCTGCCGTCGCACCCAGGCAAGCACCGCCTGCTGCACATCCACGCCAACATCCCCGGCGTGATGAGCGAGATCAACAAGGTCTTCGCCGACAACGGCATCAACGTTTCCGGCCAGTACCTGCAAACCAACGAGAAGGTCGGCTACGTAGTGATCGACGTCGATGCCGAGTACTCGGACCTGGCCCTGGAGAAACTCCAGCAGGTCAACGGTACCATCCGTAGCCGCGTGCTGTTCTAA
Protein Properties
Protein Residues: 409
Protein Molecular Weight: 44.2 kDa
Protein Theoretical pI: 6.52
Hydropathicity (GRAVY score): 0.035
Charge at pH 7 (predicted): -3.22
Protein Sequence:
>PA0316
MSKTSLDKSKIKFLLLEGVHQNAVDTLKAAGYTNIEYLKTALSGDELKERIADAHFIGIRSRTQLTEEVFDCAKKLIAVGCFCIGTNQVDLNAARERGIAVFNAPYSNTRSVAELVLAEAILLLRGIPEKNASCHRGGWIKSAANSFEIRGKKLGIVGYGSIGTQLSVLAEALGMQVFFYDTVTKLPLGNAVQIGSLHELLGMSDIVSLHVPELPSTQWMIGEKEIRAMKKGGILINAARGTVVELDHLAAAIKDEHLIGAAIDVFPVEPKSNDEEFASPLRGLDRVILTPHIGGSTAEAQANIGLEVAEKLVKYSDNGTSVSSVNFPEVALPSHPGKHRLLHIHANIPGVMSEINKVFADNGINVSGQYLQTNEKVGYVVIDVDAEYSDLALEKLQQVNGTIRSRVLF
References
External Links:
Resource Link
Genome ID: PA0316
Entrez Gene ID: 878305
NCBI Protein ID: 15595513
General Reference: PaperBLAST - Find papers about PA0316 and its homologs