Identification
Name: NAD(P) transhydrogenase subunit beta
Synonyms:
  • Nicotinamide nucleotide transhydrogenase subunit beta
  • Pyridine nucleotide transhydrogenase subunit beta
Gene Name: pntB
Enzyme Class:
Biological Properties
General Function: Involved in NAD(P)+ transhydrogenase (AB-specific) activity
Specific Function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
KEGG Reactions:
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
SMPDB Reactions:
Thumb+Thumb+ThumbThumb+Thumb
PseudoCyc/BioCyc Reactions:
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
Complex Reactions:
Thumb+Thumb+2 Thumb2 Thumb+Thumb+Thumb
Thumb+ThumbThumb+Thumb
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB001633Hydrogen ionMetaboCard
PAMDB000197NADMetaboCard
PAMDB000398NADHMetaboCard
PAMDB000089NADPMetaboCard
PAMDB000615NADPHMetaboCard
GO Classification:
Component
cell part
integral to membrane
intrinsic to membrane
membrane part
Function
binding
catalytic activity
NAD(P)+ transhydrogenase (AB-specific) activity
NAD(P)+ transhydrogenase activity
NADP or NADPH binding
nucleotide binding
oxidoreductase activity
oxidoreductase activity, acting on NADH or NADPH
oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor
Process
metabolic process
oxidation reduction
Gene Properties
Locus tag: PA0196
Strand: +
Entrez Gene ID: 878146
Accession: NP_248887.1
GI: 15595393
Sequence start: 225603
Sequence End: 227039
Sequence Length: 1436
Gene Sequence:
>PA0196
ATGAGCATGAACCTGGTCACCCTCCTGTACCTCATCGCCTCGGTCTGCTTCATCCAGGCCCTGAAAGGCCTGTCGCACCCGACCACCTCGCGCCGCGGCAACCTCTTCGGCATGGTCGGCATGGCCATCGCCGTGGCCACCACCGTCGGCCTGGTGTTCAAGCTGGGCGCGGAGATCGCCACCACCGGCGTCGGCTACATCGTCGTCGGCCTGCTGGTCGGCGGTACCGCCGGCTCAATCATGGCCAAGCGCGTCGAGATGACCAAGATGCCCGAGCTGGTCGCCTTCATGCACAGCATGATCGGCCTGGCCGCGGTGTTCATCGCCATCGCCGCGGTGGTCGAGCCGCAGTCGCTGGGGATCGTCGCGCACCTGGGCGACACCATTCCCACCGGCAACCGCCTGGAGCTGTTCCTCGGCGCGGCCATCGGCGCCATCACCTTCTCCGGTTCGGTGATCGCCTTCGGCAAGCTCTCCGGCAAGTACAAGTTTCGCCTGTTCCAGGGCACCCCGGTGCAGTTCTCCGGGCAGCACCTGCTGAACCTGGTGCTCGGCCTGGCAACCCTCGGCCTGGGCCTGGTGTTCATGTTCACCGGCAACCTCACCGCCTTCGCCGTGATGCTGGCGCTGGCCTTCGTCCTCGGCGTGCTGATCATCATCCCCATCGGCGGCGCCGACATGCCGGTGGTGGTGTCGATGCTCAACTCCTATTCCGGCTGGGCCGCGGCGGGTATCGGCTTCTCGCTGAACAACTCGATGCTGATCATCGCCGGCTCGCTGGTCGGCTCCTCGGGCGCGATCCTCTCCTACATCATGTGCAAGGCGATGAACCGCTCGTTCTTCAACGTCATCCTCGGCGGCTTCGGCGCCGAAGCCGACGCCGGCGGCCCGGCGGGCTCCAAGGAGCAGCGTCCGGTGAAGTCCGGTTCGGCCGACGATGCCTCGTTCCTGCTGACCAACGCCGACAGCGTGATCATCGTCCCCGGCTACGGCCTGGCGGTGGCCCGTGCCCAGCACGCGCTGATGGAACTGGCGGAGAAGCTGACCCATCGCGGGGTCACCGTGAAGTTCGCCATCCACCCGGTCGCCGGGCGCATGCCGGGGCACATGAACGTGCTGCTGGCCGAGGCCGAGGTGCCCTACGAGCAGGTGTTCGAGATGGAGGACATCAACTCCGAGTTCGGCCAGACCGACGTGGTCCTGGTGCTCGGTGCCAACGACGTGGTCAACCCGGCGGCGAAGAACGATCCGAAGTCGCCCATCGCCGGCATGCCGATCCTCGAGGCCTACAAGGCCAAGACCGTGATCGTCAACAAGCGCTCCATGGCCAGCGGCTACGCCGGCCTGGACAACGAGCTGTTCTACCTGGACAAGACCATGATGGTGTTCGGTGACGCCAAGAAAGTCATCGAAGACATGGTCAAGGCGGTGGAGTGA
Protein Properties
Protein Residues: 478
Protein Molecular Weight: 49.9 kDa
Protein Theoretical pI: 7.27
Hydropathicity (GRAVY score): 0.646
Charge at pH 7 (predicted): 0.86
Protein Sequence:
>PA0196
MSMNLVTLLYLIASVCFIQALKGLSHPTTSRRGNLFGMVGMAIAVATTVGLVFKLGAEIATTGVGYIVVGLLVGGTAGSIMAKRVEMTKMPELVAFMHSMIGLAAVFIAIAAVVEPQSLGIVAHLGDTIPTGNRLELFLGAAIGAITFSGSVIAFGKLSGKYKFRLFQGTPVQFSGQHLLNLVLGLATLGLGLVFMFTGNLTAFAVMLALAFVLGVLIIIPIGGADMPVVVSMLNSYSGWAAAGIGFSLNNSMLIIAGSLVGSSGAILSYIMCKAMNRSFFNVILGGFGAEADAGGPAGSKEQRPVKSGSADDASFLLTNADSVIIVPGYGLAVARAQHALMELAEKLTHRGVTVKFAIHPVAGRMPGHMNVLLAEAEVPYEQVFEMEDINSEFGQTDVVLVLGANDVVNPAAKNDPKSPIAGMPILEAYKAKTVIVNKRSMASGYAGLDNELFYLDKTMMVFGDAKKVIEDMVKAVE
References
External Links:
Resource Link
Genome ID: PA0196
Entrez Gene ID: 878146
NCBI Protein ID: 15595393
General Reference: PaperBLAST - Find papers about PA0196 and its homologs