Identification
Name: Chemotaxis response regulator protein-glutamate methylesterase
Synonyms: Not Available
Gene Name: cheB
Enzyme Class:
Biological Properties
General Function: Involved in two-component response regulator activity
Specific Function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Protein glutamate methyl ester+ThumbProtein glutamate+Thumb
Protein glutamate methyl ester + Water ↔ Protein glutamate + Methanol
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Protein L-glutamate O(5)-methyl ester+Thumbprotein L-glutamate+Thumb
Protein L-glutamate O(5)-methyl ester + Water → protein L-glutamate + Methanol
ReactionCard
Protein glutamate methyl ester+ThumbProtein glutamate+Thumb
Protein glutamate methyl ester + Water ↔ Protein glutamate + Methanol
ReactionCard
protein-L-glutamate-O4-methyl-ester+PAMDB000142Protein-alpha-L-Glutamates+PAMDB000425+PAMDB001633
protein-L-glutamate-O4-methyl-ester + Water → Protein-alpha-L-Glutamates + Methanol + Hydrogen ion
ReactionCard
Complex Reactions:
Protein L-glutamate O(5)-methyl ester+Thumbprotein L-glutamate+Thumb
Protein L-glutamate O(5)-methyl ester + Water → protein L-glutamate + Methanol
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000425MethanolMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
carboxylesterase activity
catalytic activity
hydrolase activity
hydrolase activity, acting on ester bonds
molecular transducer activity
protein methylesterase activity
protein-glutamate methylesterase activity
signal transducer activity
two-component response regulator activity
Process
biological regulation
chemotaxis
regulation of biological process
regulation of gene expression
regulation of macromolecule metabolic process
regulation of metabolic process
regulation of transcription
regulation of transcription, DNA-dependent
response to chemical stimulus
response to stimulus
signal transmission
signaling process
two-component signal transduction system (phosphorelay)
Gene Properties
Locus tag: PA0173
Strand: -
Entrez Gene ID: 882256
Accession: NP_248863.1
GI: 15595371
Sequence start: 197011
Sequence End: 198060
Sequence Length: 1049
Gene Sequence:
>PA0173
ATGCCCATCAGTGTCCTGGTCGTCGACGATTCCGCCCTGATCCGCAGCCTGCTCAAGGAGATCATCCAGGCCGACCCGGAGCTGCGCCTGGTCGGCTGCGCGCCGGACGCCTTCGTCGCCCGCGACCTGATCAAGCAGCACGCGCCGGACGTGATCAGCCTCGACGTGGAAATGCCGCGAATGGACGGCCTGACCTTCCTCGACAAGCTGATGAAGGCGCGGCCGACCCCGGTGCTGATGATCTCCTCGCTCACCGAGCGCGGTTCCGAAGCCACCCTGCGCGCGCTGGAACTGGGCGCGGTGGACTTCATCGCCAAGCCCCGGCTGGGCATCGCCGAAGGCATGCAGGCCTATGCCGAGGAAATCCGCGCCAAGCTCAAGACCGTCGCCCGCGCCCGCCTGCGCCGCCGTGCGGCGGACGCGCCGGCGCCGCCGGAAAGCGCGGCGCCGCTGCTCAGCACCGAGAAGATCATCGCCCTCGGCGCCTCCACCGGCGGCACCGAGGCGCTCAAGGAAGTGCTGCTCGGCCTGCCGGCGCACAGTCCCGGGGTGGTCATCACCCAGCACATGCCTCCCGGCTTCACCCGCAGCTTCGCCGAGCGCCTGGATCGCCTGACCCGGCTCAGCGTCAGCGAAGCGCGCGACGGCGACCGCATACTGCCCGGCCACGCCCTGGTCGCGCCGGGCGACCACCACATGGAGGTGCAGCGCTCCGGCGCCAACTACGTGGTGCGTTTGAACCGCCAGGCGCAGGTCAACGGCCACCGCCCGGCAGTGGACGTGATGTTCGAGTCGCTGGCTCGCTGCGCCGGGCGCAACCTGCTCGCCGGCCTGCTCACCGGCATGGGCAAGGACGGCGCGCGCGGGCTCCTGGCGATCCGCCAGGCCGGCGGCTACACCCTGGCCCAGGACGAGGCTACCTGCGTGGTCTACGGCATGCCCCGCGAAGCGGTGGAACTGGGCGCCGCGGAAGACGTGCTGCCGCTCGAACGGATCGCCGCCGCGCTGCTCCAGCAAGCCGCCCGGCGCGGCAGCGGCAACCGCCTCTGA
Protein Properties
Protein Residues: 349
Protein Molecular Weight: 37.3 kDa
Protein Theoretical pI: 8.49
Hydropathicity (GRAVY score): 0.011
Charge at pH 7 (predicted): 3.6
Protein Sequence:
>PA0173
MPISVLVVDDSALIRSLLKEIIQADPELRLVGCAPDAFVARDLIKQHAPDVISLDVEMPRMDGLTFLDKLMKARPTPVLMISSLTERGSEATLRALELGAVDFIAKPRLGIAEGMQAYAEEIRAKLKTVARARLRRRAADAPAPPESAAPLLSTEKIIALGASTGGTEALKEVLLGLPAHSPGVVITQHMPPGFTRSFAERLDRLTRLSVSEARDGDRILPGHALVAPGDHHMEVQRSGANYVVRLNRQAQVNGHRPAVDVMFESLARCAGRNLLAGLLTGMGKDGARGLLAIRQAGGYTLAQDEATCVVYGMPREAVELGAAEDVLPLERIAAALLQQAARRGSGNRL
References
External Links:
Resource Link
Genome ID: PA0173
Entrez Gene ID: 882256
NCBI Protein ID: 15595371
General Reference: PaperBLAST - Find papers about PA0173 and its homologs