Identification
Name: Glycyl-tRNA synthetase beta subunit
Synonyms:
  • Glycine--tRNA ligase beta subunit
  • GlyRS
Gene Name: glyS
Enzyme Class:
Biological Properties
General Function: Involved in arginine-tRNA ligase activity
Specific Function: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+tRNA(Gly)+tRNA(Gly)Thumb+Glycyl-tRNA(Gly)+Thumb+Glycyl-tRNA(Gly)
Adenosine triphosphate + Glycine + tRNA(Gly) + tRNA(Gly) ↔ Adenosine monophosphate + Glycyl-tRNA(Gly) + Pyrophosphate + Glycyl-tRNA(Gly)
ReactionCard
Thumb+Thumb+tRNA(Gly)Thumb+Thumb+Glycyl-tRNA(Gly)
SMPDB Reactions:
Thumb+Thumb+Thumb+tRNA(gly)Thumb+Pyrophosphate+Glycyl-tRNA(Gly)
Glycine + Adenosine triphosphate + Hydrogen ion + tRNA(gly) → Adenosine monophosphate + Pyrophosphate + Glycyl-tRNA(Gly)
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+tRNA(Gly)+tRNA(Gly)Thumb+Glycyl-tRNA(Gly)+Thumb+Glycyl-tRNA(Gly)
Adenosine triphosphate + Glycine + tRNA(Gly) + tRNA(Gly) ↔ Adenosine monophosphate + Glycyl-tRNA(Gly) + Pyrophosphate + Glycyl-tRNA(Gly)
ReactionCard
Thumb+Thumb+tRNA(Gly)Thumb+Thumb+Glycyl-tRNA(Gly)
Thumb+Thumb+tRNA(Gly)Thumb+Thumb+glycyl-tRNA(Gly)
Thumb+Thumb+Thumb+tRNA(gly)Thumb+Pyrophosphate+Glycyl-tRNA(Gly)
Glycine + Adenosine triphosphate + Hydrogen ion + tRNA(gly) → Adenosine monophosphate + Pyrophosphate + Glycyl-tRNA(Gly)
ReactionCard
Complex Reactions:
Thumb+Thumb+tRNA(Gly)Thumb+Thumb+glycyl-tRNA(Gly)
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000014Adenosine monophosphateMetaboCard
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000046GlycineMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000633PyrophosphateMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
aminoacyl-tRNA ligase activity
arginine-tRNA ligase activity
ATP binding
binding
catalytic activity
glycine-tRNA ligase activity
ligase activity
ligase activity, forming aminoacyl-tRNA and related compounds
ligase activity, forming carbon-oxygen bonds
nucleoside binding
nucleotide binding
purine nucleoside binding
Process
arginyl-tRNA aminoacylation
biosynthetic process
cellular macromolecule biosynthetic process
cellular macromolecule metabolic process
glycyl-tRNA aminoacylation
macromolecule biosynthetic process
macromolecule metabolic process
metabolic process
ncRNA metabolic process
RNA metabolic process
translation
tRNA aminoacylation
tRNA aminoacylation for protein translation
tRNA metabolic process
Gene Properties
Locus tag: PA0008
Strand: -
Entrez Gene ID: 878214
Accession: NP_064728.1
GI: 15595206
Sequence start: 10434
Sequence End: 12488
Sequence Length: 2054
Gene Sequence:
>PA0008
ATGAGCGCCAAGGATTTCCTGGTCGAACTGGGCACCGAAGAGCTGCCGCCAAAAGCCCTCAACAGCCTCGGCGAAGCCTTCCTCAGCGGTATCGAGAAGGGCCTCAAGGCTGCCGGTCTGAGCTATGCCGCTGCGCGTTTCTATGCGGCGCCGCGCCGTCTCGCCGTGCTGGTCGAGCAACTCGCCGTGCAGCAGCCCGACCGTACCGTCAACCTAGACGGTCCGCCGCTACAGGCCGCCTTCGACGCCAGCGGTAACCCGACCCAGGCCGCCCTGGGCTTCGCCAAGAAGTGCGGCGTGGATCTGCAGCAGATCGACAAGAGCGGTCCGAAGCTGCGCTTCATCCAGACCATCGCCGGCCAACCGGCCGCCGGCCTGCTGCCGGGCATCGTCGAGGCCTCGTTGAACGAACTGCCGATTCCCAAGCGGATGCGCTGGGCAGCTCGCCGCGAGGAGTTCGTGCGTCCGACCCAATGGCTGGTGATGCTGTTCGGCGACGATGTGGTCGAGTGCGAGATCCTCGCCCAGAAAGCCGGGCGCGAATCCCGTGGCCACCGCTTCCACAATCCGGACAATGTGCGTATTTCCAGCCCGGCAGCGTATCTGGAAGACCTGCGCGGCGCTCATGTGCTGGCCGATTTCGCCGAGCGCCGCGAGCTGATCGCCAAGCGCGTGGCCGAACTGGCCGCCGAGCAACAGGGCAGCGCCATCGTGCCGCCGAGCCTGCTCGACGAAGTGACTGCACTGGTCGAGTGGCCGGTGCCGCTGGTCTGCTCCTTCGAGGAGCGCTTCCTCGAGGTCCCGCAGGAAGCCCTGATCACCACCATGCAGGACAACCAGAAATACTTCTGCCTGCTGGACGCCAACGGCAAGCTGCTGCCTCGCTTCATCACCGTCGCCAACGTCGAGAGCAAGGCGCCGGAGAACATCGTCAGCGGTAACGAGAAGGTGGTTCGCCCGCGCCTCACCGACGCCGAGTTCTTCTTCAAGCAGGACAAGAAGCAGCCGCTCGAAAGCTTCAATGAGCGCCTGCGCAACGTAGTGTTCCAGGCCCAGCTCGGCACCGTGTTCGAGAAGGCCCAGCGCGTCTCCGGCCTGGCCGCCTACATCGCCGAACGTATAGGCGGCAATGCGCAGAACGCCTCGCGCGCCGGCATCCTGTCCAAGTGTGACCTGGCGACCGAGATGGTCGGCGAGTTCCCCGAAATGCAGGGCATCGCCGGCTACTACTACGCCACCCACGGCGGCGAAGCGGAAGACGTCGCCCTGGCCCTCAACGAGCAGTACATGCCGCGCGGCGCCGGCGCCGAGCTACCCTCGACCCTGACCGGCGCCGCCGTGGCGGTGGCCGACAAGCTCGATACCCTGGTCGGTATCTTCGGCATCGGCATGCTTCCCACCGGCAGCAAGGACCCCTACGCGCTGCGCCGCGCTGCGCTGGGCGTGCTGCGCATCCTCATCGAGAAGCAGCTCGACCTGGACCTGGTAGCCGCGGTCAACGCCGCCGTCGAGCAATACGGCGACAAGGTCAAGGCCGCCGGCCTGGCCGAGCAGGTGCTGGACTTCGTGTTCGACCGCCTGCGCGCGCGCTACGAGGACGAAGGCGTGGACGTGGCCGTGTACCAGTCGGTGCGCGCGCTCAAGCCAAGCTCGCCGCTGGACTTCGACCAGCGCGTACAGGCCGTCCAGGCCTTCCGCCAGTTGCCTGAAGCCGAGGCCCTGGCCGCGGCGAACAAACGGGTGTCGAATATTCTCGCCAAGTCCGAGGACGAGGTTCCGCCGAACGTGGATGCCAGCCTGCTGGTGGAAGCCGCCGAGAAGGCCCTGGGCAGCGCCGTGGCGAACGCCGAAAGCGAAGTCGCGCCGCTGGCAGCGGCACGCGACTATCGCGCCGCGCTGGCCCGCCTGGCGGCCTTGCGCGAGCCGGTGGATACGTTCTTCGCCGATGTGATGGTCAATGTCGACGACGCGGCGGTGCGCGCCAACCGCTATGCGCTGCTGGCCAAGCTGCGCGGGTCGTTCCTCGGGGTGGCGGACATCTCGCTGCTCGGCTGA
Protein Properties
Protein Residues: 684
Protein Molecular Weight: 74 kDa
Protein Theoretical pI: 4.84
Hydropathicity (GRAVY score): -0.032
Charge at pH 7 (predicted): -15.14
Protein Sequence:
>PA0008
MSAKDFLVELGTEELPPKALNSLGEAFLSGIEKGLKAAGLSYAAARFYAAPRRLAVLVEQLAVQQPDRTVNLDGPPLQAAFDASGNPTQAALGFAKKCGVDLQQIDKSGPKLRFIQTIAGQPAAGLLPGIVEASLNELPIPKRMRWAARREEFVRPTQWLVMLFGDDVVECEILAQKAGRESRGHRFHNPDNVRISSPAAYLEDLRGAHVLADFAERRELIAKRVAELAAEQQGSAIVPPSLLDEVTALVEWPVPLVCSFEERFLEVPQEALITTMQDNQKYFCLLDANGKLLPRFITVANVESKAPENIVSGNEKVVRPRLTDAEFFFKQDKKQPLESFNERLRNVVFQAQLGTVFEKAQRVSGLAAYIAERIGGNAQNASRAGILSKCDLATEMVGEFPEMQGIAGYYYATHGGEAEDVALALNEQYMPRGAGAELPSTLTGAAVAVADKLDTLVGIFGIGMLPTGSKDPYALRRAALGVLRILIEKQLDLDLVAAVNAAVEQYGDKVKAAGLAEQVLDFVFDRLRARYEDEGVDVAVYQSVRALKPSSPLDFDQRVQAVQAFRQLPEAEALAAANKRVSNILAKSEDEVPPNVDASLLVEAAEKALGSAVANAESEVAPLAAARDYRAALARLAALREPVDTFFADVMVNVDDAAVRANRYALLAKLRGSFLGVADISLLG
References
External Links:
Resource Link
Genome ID: PA0008
Entrez Gene ID: 878214
NCBI Protein ID: 15595206
General Reference: PaperBLAST - Find papers about PA0008 and its homologs