L-Lysyl-tRNA (PAMDB004259)

IdentificationTaxonomyPhysical PropertiesBiological PropertiesSpectraConcentrationsLinksReferencesEnzymes Transporters
Proteins (3280)
Record Information
Version 1.0
Update Date 1/22/2018 11:54:54 AM
Metabolite IDPAMDB004259
Identification
Name: L-Lysyl-tRNA
Description:L-Lysyl-tRNA is an intermediate in tRNA charging pathway in E.coli. It is a product for the enzyme lysyl-tRNA synthetase which catalyzes the reaction ATP + L-lysine + tRNALys -> AMP + diphosphate + L-lysyl-tRNALys (BioCyc class: Charged-LYS-tRNAs).
Structure
Thumb
🔍MOLSDFPDBSMILESInChIView Structure
Synonyms:
  • moco (dioxyo)
  • Molybdenum cofactor
  • Molybdenum cofactor (dioxyo)
  • Molybdopterin
  • Molybdopterin cofactor
  • MoO2(OH)DTPP-MP
  • Pterin molybdenum cofactor
Chemical Formula: C10H16MoN5O8PS2
Average Molecular Weight: 525.31
Monoisotopic Molecular Weight: 526.923197
InChI Key: VUKICSJFFDCESC-UHFFFAOYSA-L
InChI:InChI=1S/C10H14N5O6PS2.Mo.2H2O/c11-10-14-7-4(8(16)15-10)12-3-6(24)5(23)2(21-9(3)13-7)1-20-22(17,18)19;;;/h2-3,9,12,23-24H,1H2,(H2,17,18,19)(H4,11,13,14,15,16);;2*1H2/q;+2;;/p-2
CAS number: Not Available
IUPAC Name:{[(1R,10R,16R)-5-amino-7,13,13-trioxo-17-oxa-12,14-dithia-2,4,6,9-tetraaza-13-molybdatetracyclo[8.7.0.0?,??0??,???heptadeca-3(8),5,11(15)-trien-16-yl]methoxy}phosphonic acid
Traditional IUPAC Name: [(1R,10R,16R)-5-amino-7,13,13-trioxo-17-oxa-12,14-dithia-2,4,6,9-tetraaza-13-molybdatetracyclo[8.7.0.0?,??0??,???heptadeca-3(8),5,11(15)-trien-16-yl]methoxyphosphonic acid
SMILES:O.O.[Mo++].[H]C1(COP(O)([O-])=O)OC2([H])NC3=C(NC2([H])C(S)=C1S)C([O-])=NC(=N)N3
Chemical Taxonomy
Taxonomy DescriptionNot Available
Kingdom Not Available
Super ClassNot Available
Class Not Available
Sub ClassNot Available
Direct Parent Not Available
Alternative Parents Not Available
Substituents Not Available
Molecular Framework Not Available
External Descriptors Not Available
Physical Properties
State: Not Available
Charge:-2
Melting point: Not Available
Experimental Properties:
PropertyValueSource
Predicted Properties
PropertyValueSource
Water Solubility15.1 mg/mLALOGPS
logP-0.77ALOGPS
logP-2ChemAxon
logS-1.5ALOGPS
pKa (Strongest Acidic)1.32ChemAxon
pKa (Strongest Basic)0.58ChemAxon
Physiological Charge-2ChemAxon
Hydrogen Acceptor Count12ChemAxon
Hydrogen Donor Count6ChemAxon
Polar Surface Area201.67 Å2ChemAxon
Rotatable Bond Count3ChemAxon
Refractivity99.85 m3·mol-1ChemAxon
Polarizability37.28 Å3ChemAxon
Number of Rings4ChemAxon
Bioavailability0ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Biological Properties
Cellular Locations: Cytoplasm
Reactions:
Adenosine triphosphate + L-Lysine + tRNA(Lys) + tRNA(Lys) <> Adenosine monophosphate + Pyrophosphate + L-Lysyl-tRNA + L-Lysyl-tRNA
Pathways:
Spectra
Spectra:
References
References: Not Available
Synthesis Reference: Not Available
Material Safety Data Sheet (MSDS) Not Available
External Links:
ResourceLink
CHEBI ID71306
HMDB IDNot Available
Pubchem Compound ID56928099
Kegg IDC01931
ChemSpider ID28533522
Wikipedia IDNot Available
BioCyc IDNot Available

Enzymes

Protein Details
• Lysyl-tRNA synthetase
General function:
Involved in nucleotide binding
Specific function:
ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)
Gene Name:
lysS
Locus Tag:
PA3700
Molecular weight:
57.3 kDa
Reactions
ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).
Protein Details
• Uncharacterized protein YjeA
General function:
Involved in nucleotide binding
Specific function:
With YjeK might be involved in the post-translational modification of elongation factor P (EF-P)
Gene Name:
poxA
Locus Tag:
PA5513
Molecular weight:
32.4 kDa