Reaction Details
Reaction: Thumb
a [protein]-L-cysteine + a DNA containing 6-O-methylguanine = a [protein]-S-methyl-L-cysteine + DNA (without 6-O-methylguanine) + a [protein]-S-methyl-L-cysteine + DNA (without 6-O-methylguanine)
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:2.1.1.63-RXN
References:
  • Foote RS, Mitra S, Pal BC (1980). "Demethylation of O6-methylguanine in a synthetic DNA polymer by an inducible activity in Escherichia coli." Biochem Biophys Res Commun 97(2);654-9. PMID: 7008792
  • Olsson M, Lindahl T (1980). "Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue." J Biol Chem 255(22);10569-71. PMID: 7000780
  • Pegg AE, Byers TL (1992). "Repair of DNA containing O6-alkylguanine." FASEB J 6(6);2302-10. PMID: 1544541