Reaction Details
Reaction: Thumb
a holo-[acyl-carrier protein] + H2O → 4'-phosphopantetheine + an acyl-carrier protein + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:3.1.4.14-RXN
References:
  • Sobhy C (1979). "Regulation of fatty acid synthetase activity. The 4'-phosphopantetheine hydrolase of rat liver." J Biol Chem 254(17);8561-6. PMID: 224058
  • Thomas J, Cronan JE (2005). "The enigmatic acyl carrier protein phosphodiesterase of Escherichia coli: genetic and enzymological characterization." J Biol Chem 280(41);34675-83. PMID: 16107329
  • Vagelos PR, Larrabes AR (1967). "Acyl carrier protein. IX. Acyl carrier protein hydrolase." J Biol Chem 242(8);1776-81. PMID: 4290442