Reaction Details
Reaction: Thumb
a 2,3,4-saturated fatty acyl-[acp] + NADP+ ← a trans-2-enoyl-[acyl-carrier protein] + NADPH + H+
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:ENOYL-ACP-REDUCT-NADPH-RXN
References:
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  • Dugan RE, Slakey LL, Porter JW (1970). "Stereospecificity of the transfer of hydrogen from reduced nicotinamide adenine dinucleotide phosphate to the acyl chain in the dehydrogenase-catalyzed reactions of fatty acid synthesis." J Biol Chem 245(23);6312-6. PMID: 4394955
  • Heath RJ, Su N, Murphy CK, Rock CO (2000). "The enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilis." J Biol Chem 275(51);40128-33. PMID: 11007778
  • Kim KH, Park JK, Ha BH, Moon JH, Kim EE (2007). "Crystallization and preliminary X-ray crystallographic analysis of enoyl-ACP reductase III (FabL) from Bacillus subtilis." Acta Crystallogr Sect F Struct Biol Cryst Commun 63(Pt 3);246-8. PMID: 17329825
  • Kim KH, Ha BH, Kim SJ, Hong SK, Hwang KY, Kim EE (2011). "Crystal structures of Enoyl-ACP reductases I (FabI) and III (FabL) from B. subtilis." J Mol Biol 406(3);403-15. PMID: 21185310
  • Schweizer E, Kniep B, Castorph H, Holzner U (1973). "Pantetheine-free mutants of the yeast fatty-acid-synthetase complex." Eur J Biochem 39(2);353-62. PMID: 4590449
  • Stoops JK, Ross P, Arslanian MJ, Aune KC, Wakil SJ, Oliver RM (1979). "Physicochemical studies of the rat liver and adipose fatty acid synthetases." J Biol Chem 254(15);7418-26. PMID: 457689
  • Tehlivets O, Scheuringer K, Kohlwein SD (2007). "Fatty acid synthesis and elongation in yeast." Biochim Biophys Acta 1771(3);255-70. PMID: 16950653
  • Wakil SJ, Stoops JK, Joshi VC (1983). "Fatty acid synthesis and its regulation." Annu Rev Biochem 52;537-79. PMID: 6137188