Reaction Details
Reaction: Thumb
a [protein]-L-tyrosine phosphate + H2O → a [protein]-L-tyrosine + a [protein]-L-tyrosine + phosphate
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:PROTEIN-TYROSINE-PHOSPHATASE-RXN
References:
  • Foulkes JG, Howard RF, Ziemiecki A (1981). "Detection of a novel mammalian protein phosphatase with activity for phosphotyrosine." FEBS Lett 130(2);197-200. PMID: 6169552
  • Gallis B, Bornstein P, Brautigan DL (1981). "Tyrosylprotein kinase and phosphatase activities in membrane vesicles from normal and Rous sarcoma virus-transformed rat cells." Proc Natl Acad Sci U S A 78(11);6689-93. PMID: 6273884