Reaction Details
Reaction: Thumb
an N5-methyl-tetrahydrofolate + 2 an oxidized ferredoxin [iron-sulfur] cluster ← a 5,10-methylene-tetrahydrofolate + 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:RXN-5061
References:
  • Clark JE, Ljungdahl LG (1984). "Purification and properties of 5,10-methylenetetrahydrofolate reductase, an iron-sulfur flavoprotein from Clostridium formicoaceticum." J Biol Chem 259(17);10845-9. PMID: 6381490