Reaction 21906

Reaction Details
Reaction: Thumb
pyruvate + 2 an oxidized ferredoxin [iron-sulfur] cluster + coenzyme A ↔ acetyl-CoA + CO2 + 2 a reduced ferredoxin [iron-sulfur] cluster + H+
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:PYRUFLAVREDUCT-RXN
References:
  • Charon MH, Volbeda A, Chabriere E, Pieulle L, Fontecilla-Camps JC (1999). "Structure and electron transfer mechanism of pyruvate:ferredoxin oxidoreductase." Curr Opin Struct Biol 9(6);663-9. PMID: 10607667
  • Evans MC, Buchanan BB (1965). "Photoreduction of ferredoxin and its use in carbon dioxide fixation by a subcellular system from a photosynthetic bacterium." Proc Natl Acad Sci U S A 53(6);1420-5. PMID: 5217644
  • Gehring U, Arnon DI (1972). "Purification and properties of -ketoglutarate synthase from a photosynthetic bacterium." J Biol Chem 247(21);6963-9. PMID: 4628267
  • Uyeda K, Rabinowitz JC (1971). "Pyruvate-ferredoxin oxidoreductase. 3. Purification and properties of the enzyme." J Biol Chem 246(10);3111-9. PMID: 5574389
  • Uyeda K, Rabinowitz JC (1971). "Pyruvate-ferredoxin oxidoreductase. IV. Studies on the reaction mechanism." J Biol Chem 246(10);3120-5. PMID: 4324891