Reaction Details
Reaction: Thumb
a 5-L-glutamyl-[peptide] + an amino acid = a 5-L-glutamyl-amino acid + a peptide
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:GAMMA-GLUTAMYLTRANSFERASE-RXN
References:
  • Boanca G, Sand A, Okada T, Suzuki H, Kumagai H, Fukuyama K, Barycki JJ (2007). "Autoprocessing of Helicobacter pylori gamma-glutamyltranspeptidase leads to the formation of a threonine-threonine catalytic dyad." J Biol Chem 282(1);534-41. PMID: 17107958
  • Goore MY, Thompson JF (1967). "Gamma-glutamyl transpeptidase from kidney bean fruit. I. Purification and mechanism of action." Biochim Biophys Acta 132(1);15-26. PMID: 6030345
  • Leibach FH, Binkley F (1968). "Gamma-glutamyl transferase of swine kidney." Arch Biochem Biophys 127(1);92-301. PMID: 5698023
  • Okada T, Suzuki H, Wada K, Kumagai H, Fukuyama K (2006). "Crystal structures of gamma-glutamyltranspeptidase from Escherichia coli, a key enzyme in glutathione metabolism, and its reaction intermediate." Proc Natl Acad Sci U S A 103(17);6471-6. PMID: 16618936
  • Wickham S, West MB, Cook PF, Hanigan MH (2011). "Gamma-glutamyl compounds: substrate specificity of gamma-glutamyl transpeptidase enzymes." Anal Biochem 414(2);208-14. PMID: 21447318