Reaction Details
Reaction: Thumb
L-glutamate-5-semialdehyde + NAD+ + H2O → L-glutamate + NADH + 2 H+
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:RXN-14116
References:
  • Adams, E., Goldstone, A. (1960). "Hydroxyproline metabolism. IV. Enzymatic synthesis of gamma-hydroxyglutamate from Delta 1-pyrroline-3-hydroxy-5-carboxylate." J Biol Chem 235;3504-12. PMID: 13681370
  • Brown ED, Wood JM (1992). "Redesigned purification yields a fully functional PutA protein dimer from Escherichia coli." J Biol Chem 1992;267(18);13086-92. PMID: 1618807
  • Inagaki E, Ohshima N, Sakamoto K, Babayeva ND, Kato H, Yokoyama S, Tahirov TH (2007). "New insights into the binding mode of coenzymes: structure of Thermus thermophilus Delta1-pyrroline-5-carboxylate dehydrogenase complexed with NADP+." Acta Crystallogr Sect F Struct Biol Cryst Commun 63(Pt 6);462-5. PMID: 17554163
  • Nielsen E, Scainelli D, Forlani G (1997). "[delta]1-Pyrroline-5-Carboxylate Dehydrogenase from Cultured Cells of Potato (Purification and Properties)." Plant Physiol 113(4);1413-1418. PMID: 12223682