Reaction Details
Reaction: Thumb
3,4-dihydroxyphenylacetate + oxygen → 2-hydroxy-5-carboxymethylmuconate semialdehyde + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:1.13.11.15-RXN
References:
  • Adachi K, Takeda Y, Senoh S, Kita H (1964). "Metabolism of p-hydroxyphenylacetic acid in Pseudomonas ovalis." Biochim Biophys Acta 93;483-93. PMID: 14263147
  • Barbour MG, Bayly RC (1981). "Control of meta-cleavage degradation of 4-hydroxyphenylacetate in Pseudomonas putida." J Bacteriol 147(3);844-50. PMID: 6895079
  • Kutty RK, Devi NA, Veeraswamy M, Ramesh S, Rao PV (1977). "Degradation of (+/-)-synephrine by Arthrobacter synephrinum. Oxidation of 3,4-dihydroxyphenylacetate to 2-hydroxy-5-carboxymethyl-muconate semialdehyde." Biochem J 167(1);163-70. PMID: 588248