Reaction Details
Reaction: Thumb
acetyl-CoA + glyoxylate + H2O → (S)-malate + coenzyme A + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:MALSYN-RXN
References:
  • Anstrom DM, Kallio K, Remington SJ (2003). "Structure of the Escherichia coli malate synthase G:pyruvate:acetyl-coenzyme A abortive ternary complex at 1.95 A resolution." Protein Sci 12(9);1822-32. PMID: 12930982
  • Dixon GH, Kornberg HL, Lund P (1960). "Purification and properties of malate synthetase." Biochim Biophys Acta 41;217-33. PMID: 13816984
  • Molina I, Pellicer MT, Badia J, Aguilar J, Baldoma L (1994). "Molecular characterization of Escherichia coli malate synthase G. Differentiation with the malate synthase A isoenzyme." Eur J Biochem 224(2);541-8. PMID: 7925370
  • Smith CV, Huang CC, Miczak A, Russell DG, Sacchettini JC, Honer zu Bentrup K (2003). "Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis." J Biol Chem 278(3);1735-43. PMID: 12393860