Reaction Details
Reaction: Thumb
UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate + meso-diaminopimelate + ATP → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:UDP-NACMURALGLDAPLIG-RXN
References:
  • Mizuno Y, Ito E (1968). "Purification and properties of uridine diphosphate N-acetylmuramyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate ligase." J Biol Chem 243(10);2665-72. PMID: 4967958
  • van Heijenoort J (2001). "Recent advances in the formation of the bacterial peptidoglycan monomer unit." Nat Prod Rep 18(5);503-19. PMID: 11699883