Reaction Details
Reaction: Thumb
uridine + phosphate → α-D-ribose-1-phosphate + uracil
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:URPHOS-RXN
References:
  • Canellakis ES (1957). "Pyrimidine metabolism. II. Enzymatic pathways of uracil anabolism." J Biol Chem 227(1);329-38. PMID: 13449076
  • Hamamoto T, Noguchi T, Midorikawa Y (1996). "Purification and characterization of purine nucleoside phosphorylase and pyrimidine nucleoside phosphorylase from Bacillus stearothermophilus TH 6-2." Biosci Biotechnol Biochem 60(7);1179-80. PMID: 8782414
  • Leer JC, Hammer-Jespersen K, Schwartz M (1977). "Uridine phosphorylase from Escherichia coli. Physical and chemical characterization." Eur J Biochem 1977;75(1);217-24. PMID: 16751
  • Liu M, Cao D, Russell R, Handschumacher RE, Pizzorno G (1998). "Expression, characterization, and detection of human uridine phosphorylase and identification of variant uridine phosphorolytic activity in selected human tumors." Cancer Res 58(23);5418-24. PMID: 9850074
  • Okuyama K, Hamamoto T, Noguchi T, Midorikawa Y (1996). "Molecular cloning and expression of the pyrimidine nucleoside phosphorylase gene from Bacillus stearothermophilus TH 6-2." Biosci Biotechnol Biochem 60(10);1655-9. PMID: 8987664
  • Paege LM, Schlenk F (1952). "Bacterial uracil riboside phosphorylase." Arch Biochem Biophys 40(1);42-9. PMID: 12997187
  • Pontis H, Degerstedt G, Reichard P (1961). "Uridine and deoxyuridine phosphorylases from Ehrlich ascites tumor." Biochim Biophys Acta 51;138-47. PMID: 13737038
  • Pugmire MJ, Ealick SE (1998). "The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation." Structure 6(11);1467-79. PMID: 9817849
  • Saunders PP, Wilson BA, Saunders GF (1969). "Purification and comparative properties of a pyrimidine nucleoside phosphorylase from Bacillus stearothermophilus." J Biol Chem 244(13);3691-7. PMID: 4978445
  • Watanabe S, Uchida T (1995). "Cloning and expression of human uridine phosphorylase." Biochem Biophys Res Commun 216(1);265-72. PMID: 7488099