Reaction Details
Reaction: Thumb
3-octaprenyl-4-hydroxybenzoate + H+ → 2-octaprenylphenol + CO2
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:3-OCTAPRENYL-4-OHBENZOATE-DECARBOX-RXN
References:
  • Gulmezian M, Hyman KR, Marbois BN, Clarke CF, Javor GT (2007). "The role of UbiX in Escherichia coli coenzyme Q biosynthesis." Arch Biochem Biophys 467(2);144-153. PMID: 17889824
  • Leppik RA, Young IG, Gibson F (1976). "Membrane-associated reactions in ubiquinone biosynthesis in Escherichia coli. 3-Octaprenyl-4-hydroxybenzoate carboxy-lyase." Biochim Biophys Acta 1976;436(4);800-10. PMID: 782527
  • Lin F, Ferguson KL, Boyer DR, Lin XN, Marsh EN (2015). "Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by ferulic acid decarboxylase and 4-hydroxy-3-polyprenylbenzoic acid decarboxylase." ACS Chem Biol 10(4);1137-44. PMID: 25647642
  • Payne KA, White MD, Fisher K, Khara B, Bailey SS, Parker D, Rattray NJ, Trivedi DK, Goodacre R, Beveridge R, Barran P, Rigby SE, Scrutton NS, Hay S, Leys D (2015). "New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition." Nature 522(7557);497-501. PMID: 26083754
  • Pfaff C, Glindemann N, Gruber J, Frentzen M, Sadre R (2013). "Chorismate Pyruvate-Lyase and 4-Hydroxy-3-Solanesylbenzoate Decarboxylase are required for Plastoquinone Biosynthesis in the Cyanobacterium Synechocystis sp. PCC6803." J Biol Chem 289(5);2675-86. PMID: 24337576