Reaction Details
Reaction: Thumb
all-trans-undecaprenyl phosphate + UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine = undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine + UMP
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:PHOSNACMURPENTATRANSLYS-RXN
References:
  • Heydanek MG, Neuhaus FC (1969). "The initial stage in peptidoglycan synthesis. IV. Solubilization of phospho-N-acetylmuramyl-pentapeptide translocase." Biochemistry 8(4);1474-81. PMID: 5805290
  • Higashi Y, Strominger JL, Sweeley CC (1967). "Structure of a lipid intermediate in cell wall peptidoglycan synthesis: a derivative of a C55 isoprenoid alcohol." Proc Natl Acad Sci U S A 57(6);1878-84. PMID: 5231417
  • Struve WG, Sinha RK, Neuhaus FC (1966). "On the initial stage in peptidoglycan synthesis. Phospho-N-acetylmuramyl-pentapeptide translocase (uridine monophosphate)." Biochemistry 5(1);82-93. PMID: 5938956
  • van Heijenoort J (2001). "Recent advances in the formation of the bacterial peptidoglycan monomer unit." Nat Prod Rep 18(5);503-19. PMID: 11699883