Reaction Details
Reaction: Thumb
4-hydroxybenzoate + NADPH + oxygen + H+ → protocatechuate + NADP+ + H2O
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:4-HYDROXYBENZOATE-3-MONOOXYGENASE-RXN
References:
  • Hosokawa K, Stanier RY (1966). "Crystallization and properties of p-hydroxybenzoate hydroxylase from Pseudomonas putida." J Biol Chem 241(10);2453-60. PMID: 4380381
  • Howell LG, Spector T, Massey V (1972). "Purification and properties of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens." J Biol Chem 247(13);4340-50. PMID: 4402514
  • Seibold B, Matthes M, Eppink MH, Lingens F, Van Berkel WJ, Muller R (1996). "4-Hydroxybenzoate hydroxylase from Pseudomonas sp. CBS3. Purification, characterization, gene cloning, sequence analysis and assignment of structural features determining the coenzyme specificity." Eur J Biochem 239(2);469-78. PMID: 8706756
  • Spector T, Massey V (1972). "Studies on the effector specificity of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens." J Biol Chem 247(14);4679-87. PMID: 4402938
  • Spector T, Massey V (1972). "p-Hydroxybenzoate hydroxylase from Pseudomonas fluorescens. Evidence for an oxygenated flavin intermediate." J Biol Chem 247(17);5632-6. PMID: 4403446
  • Spector T, Massey V (1972). "p-Hydroxybenzoate hydroxylase from Pseudomonas fluorescens. Reactivity with oxygen." J Biol Chem 247(22);7123-7. PMID: 4404745