Reaction Details
Reaction: Thumb
(R)-2,3-dihydroxy-3-methylpentanoate + NADP+ ← (S)-2-aceto-2-hydroxybutanoate + NADPH + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:ACETOOHBUTREDUCTOISOM-RXN
References:
  • Arfin SM, Umbarger HE (1969). "Purification and properties of the acetohydroxy acid isomeroreductase of Salmonella typhimurium." J Biol Chem 244(5);1118-27. PMID: 4388025
  • Satyanarayana T, Radhakrishnan AN (1965). "Biosynthesis of valine and isoleucine in plants. 3. Reductoisomerase of Phaseolus radiatus." Biochim Biophys Acta 110(2);380-8. PMID: 5866387