Reaction Details
Reaction: Thumb
(deoxynucleotides)(m) + (deoxynucleotides)(n) + NAD+ → (deoxynucleotides)(n+m) + β-nicotinamide D-ribonucleotide + AMP
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:DNA-LIGASE-NAD%2b-RXN
References:
  • Kim YJ, Lee HS, Bae SS, Jeon JH, Yang SH, Lim JK, Kang SG, Kwon ST, Lee JH (2006). "Cloning, expression, and characterization of a DNA ligase from a hyperthermophilic archaeon Thermococcus sp." Biotechnol Lett 28(6);401-7. PMID: 16614906
  • Rolland JL, Gueguen Y, Persillon C, Masson JM, Dietrich J (2004). "Characterization of a thermophilic DNA ligase from the archaeon Thermococcus fumicolans." FEMS Microbiol Lett 236(2);267-73. PMID: 15251207