Reaction Details
Reaction: Thumb
dUTP + H2O → dUMP + diphosphate + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:DUTP-PYROP-RXN
References:
  • BERTANI LE, HAEGGMARK A, REICHARD P (1963). "ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOTIDES. II. FORMATION AND INTERCONVERSION OF DEOXYURIDINE PHOSPHATES." J Biol Chem 238;3407-13. PMID: 14085395
  • Chern CJ, MacDonald AB, Morris AJ (1969). "Purification and properties of a nucleoside triphosphate pyrophosphohydrolase from red cells of the rabbit." J Biol Chem 244(20);5489-95. PMID: 4310599
  • Giroir LE, Deutsch WA (1987). "Drosophila deoxyuridine triphosphatase. Purification and characterization." J Biol Chem 262(1);130-4. PMID: 3025197
  • GREENBERG GR, SOMERVILLE RL (1962). "Deoxyuridylate kinase activity and deoxyuridinetriphosphatase in Escherichia coli." Proc Natl Acad Sci U S A 48;247-57. PMID: 13901467
  • Grindey GR, Nichol CA (1971). "Mammalian deoxyuridine 5'-triphosphate pyrophosphatase." Biochim Biophys Acta 240(2);180-3. PMID: 5105331
  • Zhang J, Inouye M (2002). "MazG, a nucleoside triphosphate pyrophosphohydrolase, interacts with Era, an essential GTPase in Escherichia coli." J Bacteriol 184(19);5323-9. PMID: 12218018